Improvements of a Laboratory Phase-Contrast Nano-Computed Tomography System

Patrick Ilg, Oliver Schurius, Martin Dierolf, Benedikt Günther, Franz Pfeiffer

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

Nano Computed Tomography (nanoCT) is a powerful tool for non-destructive three-dimensional specimen visualization and investigation at the submicron scale. Here, we present our lensless lab-based nanoCT setup, which combines a nanofocus X-ray source with a photon-counting detector. On the one hand, the X-ray source’s coherence enables propagation-based phase-contrast, which is beneficial for investigating low-absorbing specimens, e.g., in virtual 3D-histology of biopsies and material science. We describe the setup, discuss its optimization, focusing on acquisition speed and field of view increase, and present the latest results.

Original languageEnglish
Title of host publicationDevelopments in X-Ray Tomography XV
EditorsBert Muller, Ge Wang
PublisherSPIE
ISBN (Electronic)9781510679641
DOIs
StatePublished - 2024
Event15th SPIE Conference on Developments in X-Ray Tomography - San Diego, United States
Duration: 19 Aug 202422 Aug 2024

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume13152
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

Conference15th SPIE Conference on Developments in X-Ray Tomography
Country/TerritoryUnited States
CitySan Diego
Period19/08/2422/08/24

Keywords

  • nano computed tomography
  • nanofocus source
  • photon-counting detector
  • propagation-based phase-contrast
  • virtual histology

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