TY - JOUR
T1 - Impact of transcatheter aortic valve implantation on surgical aortic valve
AU - Vaquerizo, Beatriz
AU - Bleiziffer, Sabine
AU - Wottke, Michael
AU - Spaziano, Marco
AU - Eschenbach, Lena
AU - Lange, Rüdiger
AU - Piazza, Nicolo
N1 - Publisher Copyright:
© 2017
PY - 2017/9/15
Y1 - 2017/9/15
N2 - Introduction and objectives TAVR is thought to change the volumes, characteristics, and outcomes of patients with aortic stenosis undergoing SAVR. We sought to investigate the impact of increasing transcatheter aortic valve replacement (TAVR) volumes on surgical aortic valve replacement (SAVR) volumes and to assess the evolution in baseline demographics and its impact on 30-day clinical outcomes across TAVR and SAVR patients. Methods From June 2007 through September 2015, 3543 consecutive patients with severe aortic stenosis who underwent TAVR (n = 1407) or SAVR (n = 2136) in a single center were subcategorized into nine cohorts defined by procedure year. These cohorts were examined for differences in volumes, baseline demographics, and 30-day mortality. Results We observed a reduction in SAVR compared to TAVR volumes over time: from 79% in 2007 to 48% in 2015 (P < 0.001). The mean STS score of the TAVR patients decreased significantly from 6.8 in 2007 to 4.3 in 2015 (P < 0.001). Concurrently, the crude 30-day mortality for TAVR improved from 11% in 2007 to 3% in 2015 (P < 0.001). The overall 30-day mortality was similar between TAVR and SAVR after adjusting for the independent predictors of mortality (adjusted odds ratio (OR) = 0.758; P = 0.2). Conclusions In a high-volume surgical center, we observed a significant decrease in patients undergoing SAVR compared to TAVR. We show an important shift toward the selection of lower surgical risk patients for TAVR. Overall 30-day mortality was similar between TAVR and SAVR after adjusting for baseline characteristics.
AB - Introduction and objectives TAVR is thought to change the volumes, characteristics, and outcomes of patients with aortic stenosis undergoing SAVR. We sought to investigate the impact of increasing transcatheter aortic valve replacement (TAVR) volumes on surgical aortic valve replacement (SAVR) volumes and to assess the evolution in baseline demographics and its impact on 30-day clinical outcomes across TAVR and SAVR patients. Methods From June 2007 through September 2015, 3543 consecutive patients with severe aortic stenosis who underwent TAVR (n = 1407) or SAVR (n = 2136) in a single center were subcategorized into nine cohorts defined by procedure year. These cohorts were examined for differences in volumes, baseline demographics, and 30-day mortality. Results We observed a reduction in SAVR compared to TAVR volumes over time: from 79% in 2007 to 48% in 2015 (P < 0.001). The mean STS score of the TAVR patients decreased significantly from 6.8 in 2007 to 4.3 in 2015 (P < 0.001). Concurrently, the crude 30-day mortality for TAVR improved from 11% in 2007 to 3% in 2015 (P < 0.001). The overall 30-day mortality was similar between TAVR and SAVR after adjusting for the independent predictors of mortality (adjusted odds ratio (OR) = 0.758; P = 0.2). Conclusions In a high-volume surgical center, we observed a significant decrease in patients undergoing SAVR compared to TAVR. We show an important shift toward the selection of lower surgical risk patients for TAVR. Overall 30-day mortality was similar between TAVR and SAVR after adjusting for baseline characteristics.
KW - Severe aortic stenosis
KW - Surgical aortic valve replacement
KW - Transcatheter aortic valve replacement
KW - Valvular heart disease
UR - http://www.scopus.com/inward/record.url?scp=85019842528&partnerID=8YFLogxK
U2 - 10.1016/j.ijcard.2017.05.074
DO - 10.1016/j.ijcard.2017.05.074
M3 - Article
C2 - 28536003
AN - SCOPUS:85019842528
SN - 0167-5273
VL - 243
SP - 145
EP - 149
JO - International Journal of Cardiology
JF - International Journal of Cardiology
ER -