Immunsuppressive Medikamente in der Therapie nach Nierentransplantation

Translated title of the contribution: Immunosuppressants in the treatment of kidney transplant recipients

L. Renders, U. Kunzendorf

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Currently two calcineurin inhibitors (cyclosporin A, tacrolimus), three DNA synthesis inhibitors (mycophenolate, mycophenolatmofetil, azathioprin) and two TOR inhibitors (everolimus, sirolimus) are used for immunosuppressant therapy in kidney transplant recipients. Steroids and different types of antibodies may extend immunosuppressant regimens. The present article discusses pharmacokinetic data, adverse effects and interaction profiles of these drugs and the possibilities opened up by various combinations in current use and their limitations; it also deals with current guidelines on treating rejection.

Translated title of the contributionImmunosuppressants in the treatment of kidney transplant recipients
Original languageGerman
Pages (from-to)157-166
Number of pages10
JournalNephrologe
Volume2
Issue number3
DOIs
StatePublished - May 2007
Externally publishedYes

Fingerprint

Dive into the research topics of 'Immunosuppressants in the treatment of kidney transplant recipients'. Together they form a unique fingerprint.

Cite this