Immunology

Martin Röcken; Beatrix Evers; Tilo Biedermann

doi:10.1007/978-3-662-63709-8_2

Immunology

Martin Röcken
, Beatrix Evers
, Tilo Biedermann

Medicine and Health

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

The skin is a complex organ that harbors a multitude of different cell types and protects the body from external insults. During the past decade, we have gained important insight into the dynamic interplay between immune and non-immune cells required to protect the skin from physical stress, toxins, and pathogens, while maintaining self-tolerance. Even minute dysregulation of this interplay can lead to allergy, autoimmunity, and cancer formation, with detrimental consequences. A thorough understanding of skin immunity therefore facilitates an understanding of the pathophysiology of skin diseases as well as the implementation of innovative treatment concepts.

Original language	English
Title of host publication	Braun-Falco's Dermatology
Publisher	Springer Berlin Heidelberg
Pages	23-34
Number of pages	12
ISBN (Print)	9783662637098
DOIs	https://doi.org/10.1007/978-3-662-63709-8_2
State	Published - 27 Apr 2022

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1007/978-3-662-63709-8_2

Cite this

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AU - Evers, Beatrix

AU - Biedermann, Tilo

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N2 - The skin is a complex organ that harbors a multitude of different cell types and protects the body from external insults. During the past decade, we have gained important insight into the dynamic interplay between immune and non-immune cells required to protect the skin from physical stress, toxins, and pathogens, while maintaining self-tolerance. Even minute dysregulation of this interplay can lead to allergy, autoimmunity, and cancer formation, with detrimental consequences. A thorough understanding of skin immunity therefore facilitates an understanding of the pathophysiology of skin diseases as well as the implementation of innovative treatment concepts.

AB - The skin is a complex organ that harbors a multitude of different cell types and protects the body from external insults. During the past decade, we have gained important insight into the dynamic interplay between immune and non-immune cells required to protect the skin from physical stress, toxins, and pathogens, while maintaining self-tolerance. Even minute dysregulation of this interplay can lead to allergy, autoimmunity, and cancer formation, with detrimental consequences. A thorough understanding of skin immunity therefore facilitates an understanding of the pathophysiology of skin diseases as well as the implementation of innovative treatment concepts.

UR - https://www.scopus.com/pages/publications/85158946963

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M3 - Chapter

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SN - 9783662637098

SP - 23

EP - 34

BT - Braun-Falco's Dermatology

PB - Springer Berlin Heidelberg

ER -

Immunology

Abstract

UN SDGs

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