Abstract
17 cases of clinical incompatibility reactions due to human serum albumin were examined. The reactions consisted of tachycardia, fever, exanthema and hypotension. Regarding the onset of time, 'early' and 'late' reactions were distinguished. Impurities in the administered albumin batches as etiologic factor was excluded. The results of immunodiffusion, antigen elimination and skin tests suggest a pathogenetic influence of immunological reactions. The application of further purified albumin solutions might possibly reduce the frequency of incompatibility reactions.
| Translated title of the contribution | Immunologic evaluation of patients with clinical incompatibility of human albumin |
|---|---|
| Original language | German |
| Pages (from-to) | 411-415 |
| Number of pages | 5 |
| Journal | Langenbecks Archiv für Chirurgie |
| Volume | Sup. 1975 |
| State | Published - 1975 |
| Externally published | Yes |