Imaging with dual-interfering sources

X. Intes; V. Ntziachristos; A. G. Yodh; B. Chance

doi:10.1117/12.434471

Imaging with dual-interfering sources

X. Intes, V. Ntziachristos, A. G. Yodh, B. Chance

University of Pennsylvania

Research output: Contribution to journal › Conference article › peer-review

1 Scopus citations

Abstract

Dual interfering source systems have been shown to be more sensitive to the presence of absorbing inhomogeneities than single-source systems. They are used to localize accurately deep inhomogeneities with backprojection methods. However, there is not actually a method to perform indirect imaging with such techniques. In this work, a tomographic reconstruction method for an absorbing perturbation in highly scattering media and for phased array system is derived. The perturbation approach to solve the hetexogeneous diffusion equation is used with the first order Rytov expansion. Analytical weight functions necessary to solve the inverse problem are obtained. Validity of the derived analytical expressions was checked with reconstructions from simulated data obtained with finite difference solutions of the diffusion equation and for a media mimicking breast tissue.

Original language	English
Pages (from-to)	68-75
Number of pages	8
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	4250
DOIs	https://doi.org/10.1117/12.434471
State	Published - 2001
Externally published	Yes
Event	Optical Tomography and Spectroscopy of Tissue IV - San Jose, CA, United States Duration: 21 Jan 2001 → 23 Jan 2001

Access to Document

10.1117/12.434471

Cite this

@article{e31b35eeb77843879b5e9603a9a1f7a1,

title = "Imaging with dual-interfering sources",

abstract = "Dual interfering source systems have been shown to be more sensitive to the presence of absorbing inhomogeneities than single-source systems. They are used to localize accurately deep inhomogeneities with backprojection methods. However, there is not actually a method to perform indirect imaging with such techniques. In this work, a tomographic reconstruction method for an absorbing perturbation in highly scattering media and for phased array system is derived. The perturbation approach to solve the hetexogeneous diffusion equation is used with the first order Rytov expansion. Analytical weight functions necessary to solve the inverse problem are obtained. Validity of the derived analytical expressions was checked with reconstructions from simulated data obtained with finite difference solutions of the diffusion equation and for a media mimicking breast tissue.",

author = "X. Intes and V. Ntziachristos and Yodh, {A. G.} and B. Chance",

year = "2001",

doi = "10.1117/12.434471",

language = "English",

volume = "4250",

pages = "68--75",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

issn = "0277-786X",

publisher = "SPIE",

note = "Optical Tomography and Spectroscopy of Tissue IV ; Conference date: 21-01-2001 Through 23-01-2001",

}

TY - JOUR

T1 - Imaging with dual-interfering sources

AU - Intes, X.

AU - Ntziachristos, V.

AU - Yodh, A. G.

AU - Chance, B.

PY - 2001

Y1 - 2001

N2 - Dual interfering source systems have been shown to be more sensitive to the presence of absorbing inhomogeneities than single-source systems. They are used to localize accurately deep inhomogeneities with backprojection methods. However, there is not actually a method to perform indirect imaging with such techniques. In this work, a tomographic reconstruction method for an absorbing perturbation in highly scattering media and for phased array system is derived. The perturbation approach to solve the hetexogeneous diffusion equation is used with the first order Rytov expansion. Analytical weight functions necessary to solve the inverse problem are obtained. Validity of the derived analytical expressions was checked with reconstructions from simulated data obtained with finite difference solutions of the diffusion equation and for a media mimicking breast tissue.

AB - Dual interfering source systems have been shown to be more sensitive to the presence of absorbing inhomogeneities than single-source systems. They are used to localize accurately deep inhomogeneities with backprojection methods. However, there is not actually a method to perform indirect imaging with such techniques. In this work, a tomographic reconstruction method for an absorbing perturbation in highly scattering media and for phased array system is derived. The perturbation approach to solve the hetexogeneous diffusion equation is used with the first order Rytov expansion. Analytical weight functions necessary to solve the inverse problem are obtained. Validity of the derived analytical expressions was checked with reconstructions from simulated data obtained with finite difference solutions of the diffusion equation and for a media mimicking breast tissue.

UR - http://www.scopus.com/inward/record.url?scp=0034870983&partnerID=8YFLogxK

U2 - 10.1117/12.434471

DO - 10.1117/12.434471

M3 - Conference article

AN - SCOPUS:0034870983

SN - 0277-786X

VL - 4250

SP - 68

EP - 75

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

T2 - Optical Tomography and Spectroscopy of Tissue IV

Y2 - 21 January 2001 through 23 January 2001

ER -

Imaging with dual-interfering sources

Abstract

Access to Document

Other files and links

Fingerprint

Cite this