TY - GEN
T1 - Imaging the small animal cardiovascular system in real-time with Multispectral Optoacoustic Tomography
AU - Taruttis, Adrian
AU - Herzog, Eva
AU - Razansky, Daniel
AU - Ntziachristos, Vasilis
PY - 2011
Y1 - 2011
N2 - Multispectral Optoacoustic Tomography (MSOT) is an emerging technique for high resolution macroscopic imaging with optical and molecular contrast. We present cardiovascular imaging results from a multi-element real-time MSOT system recently developed for studies on small animals. Anatomical features relevant to cardiovascular disease, such as the carotid arteries, the aorta and the heart, are imaged in mice. The system's fast acquisition time, in tens of microseconds, allows images free of motion artifacts from heartbeat and respiration. Additionally, we present in-vivo detection of optical imaging agents, gold nanorods, at high spatial and temporal resolution, paving the way for molecular imaging applications.
AB - Multispectral Optoacoustic Tomography (MSOT) is an emerging technique for high resolution macroscopic imaging with optical and molecular contrast. We present cardiovascular imaging results from a multi-element real-time MSOT system recently developed for studies on small animals. Anatomical features relevant to cardiovascular disease, such as the carotid arteries, the aorta and the heart, are imaged in mice. The system's fast acquisition time, in tens of microseconds, allows images free of motion artifacts from heartbeat and respiration. Additionally, we present in-vivo detection of optical imaging agents, gold nanorods, at high spatial and temporal resolution, paving the way for molecular imaging applications.
KW - Molecular imaging
KW - Optical imaging
KW - Optoacoustic tomography
KW - Photoacoustic imaging
KW - Small animal imaging
UR - http://www.scopus.com/inward/record.url?scp=79955491228&partnerID=8YFLogxK
U2 - 10.1117/12.874242
DO - 10.1117/12.874242
M3 - Conference contribution
AN - SCOPUS:79955491228
SN - 9780819484369
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Photons Plus Ultrasound
T2 - Photons Plus Ultrasound: Imaging and Sensing 2011
Y2 - 23 January 2011 through 25 January 2011
ER -