IL-6 and G-CSF levels in amniotic fluid during the second trimester in normal and abnormal pregnancies

E. Weimann; G. Reisbach; J. Reinsberg; M. J. Lentze

doi:10.1007/BF01314640

IL-6 and G-CSF levels in amniotic fluid during the second trimester in normal and abnormal pregnancies

E. Weimann, G. Reisbach, J. Reinsberg, M. J. Lentze

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13 Scopus citations

Abstract

Activity levels of cytokines were measured by stimulation of the cell lines NFS-60, 7TD1, and TF-1. In 39 samples of amniotic fluid, levels of Granulocyte-Stimulating Factor (G-CSF) were 1434±2063 (mean±SD) and of Interleukin (IL-6) 546±1071 pg/ml; Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was not detectable. IL-6 was correlated to G-CSF (r=0.3; p=0.003). G-CSF (p=0.0002) and IL-6 (p=0.006) were influenced by Alpha-Fetoprotein (AFP) and G-CSF by rhesus-incompatibility (p=0.0004). These findings suggest that cytokines such as IL-6 and G-CSF play some role in physiological and pathological pregnancy.

Original language	English
Pages (from-to)	125-130
Number of pages	6
Journal	Archives of Gynecology and Obstetrics
Volume	256
Issue number	3
DOIs	https://doi.org/10.1007/BF01314640
State	Published - Sep 1995
Externally published	Yes

Keywords

Alpha-fetoprotein
Amniotic fluid
Cytokines
Rhesus incompatibility

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10.1007/BF01314640

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title = "IL-6 and G-CSF levels in amniotic fluid during the second trimester in normal and abnormal pregnancies",

abstract = "Activity levels of cytokines were measured by stimulation of the cell lines NFS-60, 7TD1, and TF-1. In 39 samples of amniotic fluid, levels of Granulocyte-Stimulating Factor (G-CSF) were 1434±2063 (mean±SD) and of Interleukin (IL-6) 546±1071 pg/ml; Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was not detectable. IL-6 was correlated to G-CSF (r=0.3; p=0.003). G-CSF (p=0.0002) and IL-6 (p=0.006) were influenced by Alpha-Fetoprotein (AFP) and G-CSF by rhesus-incompatibility (p=0.0004). These findings suggest that cytokines such as IL-6 and G-CSF play some role in physiological and pathological pregnancy.",

keywords = "Alpha-fetoprotein, Amniotic fluid, Cytokines, Rhesus incompatibility",

author = "E. Weimann and G. Reisbach and J. Reinsberg and Lentze, {M. J.}",

year = "1995",

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T1 - IL-6 and G-CSF levels in amniotic fluid during the second trimester in normal and abnormal pregnancies

AU - Weimann, E.

AU - Reisbach, G.

AU - Reinsberg, J.

AU - Lentze, M. J.

PY - 1995/9

Y1 - 1995/9

N2 - Activity levels of cytokines were measured by stimulation of the cell lines NFS-60, 7TD1, and TF-1. In 39 samples of amniotic fluid, levels of Granulocyte-Stimulating Factor (G-CSF) were 1434±2063 (mean±SD) and of Interleukin (IL-6) 546±1071 pg/ml; Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was not detectable. IL-6 was correlated to G-CSF (r=0.3; p=0.003). G-CSF (p=0.0002) and IL-6 (p=0.006) were influenced by Alpha-Fetoprotein (AFP) and G-CSF by rhesus-incompatibility (p=0.0004). These findings suggest that cytokines such as IL-6 and G-CSF play some role in physiological and pathological pregnancy.

AB - Activity levels of cytokines were measured by stimulation of the cell lines NFS-60, 7TD1, and TF-1. In 39 samples of amniotic fluid, levels of Granulocyte-Stimulating Factor (G-CSF) were 1434±2063 (mean±SD) and of Interleukin (IL-6) 546±1071 pg/ml; Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was not detectable. IL-6 was correlated to G-CSF (r=0.3; p=0.003). G-CSF (p=0.0002) and IL-6 (p=0.006) were influenced by Alpha-Fetoprotein (AFP) and G-CSF by rhesus-incompatibility (p=0.0004). These findings suggest that cytokines such as IL-6 and G-CSF play some role in physiological and pathological pregnancy.

KW - Alpha-fetoprotein

KW - Amniotic fluid

KW - Cytokines

KW - Rhesus incompatibility

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ER -

IL-6 and G-CSF levels in amniotic fluid during the second trimester in normal and abnormal pregnancies

Abstract

Keywords

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