Hybrid spherical array for combined volumetric optoacoustic and B-mode ultrasound imaging

Hsiao Chun Amy Lin, Xosé Luís Deán-Ben, Ali Ozbek, Yi Hsuan Shao, Berkan Lafci, Daniel Razansky

Research output: Contribution to journalLetterpeer-review

1 Scopus citations


Optoacoustic (OA) imaging has achieved tremendous progress with state-of-the-art systems providing excellent functional and molecular contrast, centimeter scale penetration into living tissues, and ultrafast imaging performance, making it highly suitable for handheld imaging in the clinics. OA can greatly benefit from efficient integration with ultrasound (US) imaging, which remains the routine method in bedside clinical diagnostics. However, such integration has not been straightforward since the two modalities typically involve different image acquisition strategies. Here, we present a new, to our knowledge, hybrid optoacoustic ultrasound (OPUS) imaging approach employing a spherical array with dedicated segments for each modality to enable volumetric OA imaging merged with conventional B-mode US. The system performance is subsequently showcased in healthy human subjects. The new OPUS approach hence represents an important step toward establishing OA in point-of-care diagnostic settings.

Original languageEnglish
Pages (from-to)1469-1472
Number of pages4
JournalOptics Letters
Issue number6
StatePublished - 15 Mar 2024
Externally publishedYes


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