Hybrid multiphoton and optoacoustic microscope

George J. Tserevelakis; Dominik Soliman; Murad Omar; Vasilis Ntziachristos

doi:10.1364/OL.39.001819

Hybrid multiphoton and optoacoustic microscope

George J. Tserevelakis, Dominik Soliman, Murad Omar, Vasilis Ntziachristos

Chair of Biological Imaging

Technical University of Munich

Research output: Contribution to journal › Article › peer-review

53 Scopus citations

Abstract

We present a hybrid microscope combining multiphoton microscopy incorporating second-harmonic generation contrast and optical-resolution optoacoustic (photoacoustic) microscopy. We study the relative performance of the two systems and investigate the complementarity of contrast by demonstrating the label-free imaging capabilities of the hybrid microscope on zebrafish larvae ex vivo, concurrently visualizing the fish musculature and melanocytes. This implementation can prove useful in multiparametric microscopy studies, enabling broader information to be collected from biological specimens.

Original language	English
Pages (from-to)	1819-1822
Number of pages	4
Journal	Optics Letters
Volume	39
Issue number	7
DOIs	https://doi.org/10.1364/OL.39.001819
State	Published - 1 Apr 2014

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Hybrid multiphoton and optoacoustic microscope

Abstract

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