Hosting of ProteomicsDB at the HPI

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

ProteomicsDB1 is a protein-centric in-memory database for the exploration of large collections of quantitative mass spectrometry-based proteomics data. To date, it contains quantitative data from over 19k LC-MS/MS experiments covering more than 200 tissues, body fluids and cell lines. We extended the data model to enable the storage and integrated visualization of other quantitative omics data. This includes transcriptomics data from e. g. NCBI GEO, protein-protein interaction information from STRING, functional annotations from KEGG, drug-sensitivity/selectivity data from several public sources and reference mass spectra from the ProteomeTools project. The extended functionality transforms ProteomicsDB into a multipurpose resource connecting quantification and meta-data for each protein. The rich user interface helps researchers to navigate all data sources in either a protein-centric or multi-protein-centric manner.

Original languageEnglish
Title of host publicationHPI Future SOC Lab - Proceedings 2017
EditorsChristoph Meinel, Andreas Polze, Karsten Beins, Rolf Strotmann, Ulrich Seibold, Kurt Rodszus, Jurgen Muller
PublisherUniversitatsverlag Potsdam
Pages223-229
Number of pages7
ISBN (Electronic)9783869564753
StatePublished - 2019
EventHPI Future SOC Lab 2017 - Potsdam, Germany
Duration: 15 Nov 2017 → …

Publication series

NameTechnische Berichte des Hasso-Plattner-Instituts fur Softwaresystemtechnik an der Universitat Potsdam
Volume130
ISSN (Print)2191-1665
ISSN (Electronic)1613-5652

Conference

ConferenceHPI Future SOC Lab 2017
Country/TerritoryGermany
CityPotsdam
Period15/11/17 → …

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