High resolution laboratory grating-based x-ray phase-contrast CT

Manuel P. Viermetz, Lorenz J.B. Birnbacher, Andreas Fehringer, Marian Willner, Peter B. Noel, Franz Pfeiffer, Julia Herzen

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

Grating-based phase-contrast computed tomography (gbPC-CT) is a promising imaging method for imaging of soft tissue contrast without the need of any contrast agent. The focus of this study is the increase in spatial resolution without loss in sensitivity to allow visualization of pathologies comparable to the convincing results obtained at the synchrotron. To improve the effective pixel size a super-resolution reconstruction based on subpixel shifts involving a deconvolution of the image is applied on differential phase-contrast data. In our study we could achieve an effective pixel sizes of 28mm without any drawback in terms of sensitivity or the ability to measure quantitative data.

Original languageEnglish
Title of host publicationMedical Imaging 2017
Subtitle of host publicationPhysics of Medical Imaging
EditorsTaly Gilat Schmidt, Joseph Y. Lo, Thomas G. Flohr
PublisherSPIE
ISBN (Electronic)9781510607095
DOIs
StatePublished - 2017
EventMedical Imaging 2017: Physics of Medical Imaging - Orlando, United States
Duration: 13 Feb 201716 Feb 2017

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10132
ISSN (Print)1605-7422

Conference

ConferenceMedical Imaging 2017: Physics of Medical Imaging
Country/TerritoryUnited States
CityOrlando
Period13/02/1716/02/17

Keywords

  • CT
  • Grating-based phase-contrast computed tomography
  • High Resolution

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