High-grade supraclavicular soft tissue sarcoma as secondary malignancy after successful treatment of acute myeloid leukemia: Case report and literature review

Matthias Troeltzsch, Herbert Stimmer, Rupert Langer, Markus Troeltzsch, Timm Steiner, Klaus Dietrich Wolff

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1 Scopus citations

Abstract

It is well known that the treatment protocols for hematopoetic neoplasms carry a high risk of long-term oncogenicity. However, few reports have been published of sarcomas as secondary malignancies. An unusual case report of a soft tissue sarcoma appearing as a secondary cancer is presented, with a review of the published data. The present report involves a soft tissue sarcoma of the neck that occurred 18 years after curative treatment of acute myeloid leukemia by induction chemotherapy and bone marrow transplantation. Consecutive graft-versus-host disease affected the cervical skin. Soft tissue sarcomas appearing as secondary tumors are rare in oncology. The presented case describes the appearance of a sarcoma 18 years after curative treatment of acute myeloid leukemia. This is only the second case of this type reported in published studies.

Original languageEnglish
Pages (from-to)2211-2217
Number of pages7
JournalJournal of Oral and Maxillofacial Surgery
Volume70
Issue number9
DOIs
StatePublished - Sep 2012

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