TY - GEN
T1 - High Frequency QRS Analysis from Orthogonal Leads
AU - Halamek, Josef
AU - Leinveber, Pavel
AU - Malik, Marek
AU - Schmidt, Georg
AU - Plesinger, Filip
AU - Matejkova, Magdalena
AU - Lipoldova, Jolana
AU - Jurak, Pavel
N1 - Publisher Copyright:
© 2018 Creative Commons Attribution.
PY - 2018/9
Y1 - 2018/9
N2 - We analysed high frequency averaged QRS (HFQRS) in orthogonal leads and different passbands. Three groups of subjects were compared: healthy subjects, ischemic heart disease (IHD) and dilated cardiomyopathy (DCM) patients. Among the IHD group, those with heart failure (HF) symptoms were identified. Investigated parameters included HFQRS maximal amplitude, HFQRS power, and HFQRS fragmentation based on normalized length of the HFQRS line. The study aimed at assessing (1) group differences in relation to the passband, lead, and parameter, and (2) the reproducibility of parameters. Results: Significant differences were found between healthy subjects and IHD or DCM in all parameters and passbands. Some singularities of significance existed between IHD and DCM. Significant differences were also found between IHD sub-groups with and without HF symptoms, and these existed over more frequency bands. Conclusion: HFQRS parameters are frequency dependent and this dependency should be tested to eliminate singularities in statistical significances. Differences between groups with or without HF symptoms were found mainly at higher passbands, regardless of deterioration of reproducibility. Lead X appeared to be the lead with maximal differences between groups.
AB - We analysed high frequency averaged QRS (HFQRS) in orthogonal leads and different passbands. Three groups of subjects were compared: healthy subjects, ischemic heart disease (IHD) and dilated cardiomyopathy (DCM) patients. Among the IHD group, those with heart failure (HF) symptoms were identified. Investigated parameters included HFQRS maximal amplitude, HFQRS power, and HFQRS fragmentation based on normalized length of the HFQRS line. The study aimed at assessing (1) group differences in relation to the passband, lead, and parameter, and (2) the reproducibility of parameters. Results: Significant differences were found between healthy subjects and IHD or DCM in all parameters and passbands. Some singularities of significance existed between IHD and DCM. Significant differences were also found between IHD sub-groups with and without HF symptoms, and these existed over more frequency bands. Conclusion: HFQRS parameters are frequency dependent and this dependency should be tested to eliminate singularities in statistical significances. Differences between groups with or without HF symptoms were found mainly at higher passbands, regardless of deterioration of reproducibility. Lead X appeared to be the lead with maximal differences between groups.
UR - http://www.scopus.com/inward/record.url?scp=85068792529&partnerID=8YFLogxK
U2 - 10.22489/CinC.2018.051
DO - 10.22489/CinC.2018.051
M3 - Conference contribution
AN - SCOPUS:85068792529
T3 - Computing in Cardiology
BT - Computing in Cardiology Conference, CinC 2018
PB - IEEE Computer Society
T2 - 45th Computing in Cardiology Conference, CinC 2018
Y2 - 23 September 2018 through 26 September 2018
ER -