Hepatitis C virus genotypes in Hungarian and Austrian patients with chronic hepatitis C

Zsófia Müller; Judith Deák; R. Stefan Ross; Elisabeth Nagy; László Kovács; M. Roggendorf; Harald H. Kessler

doi:10.1016/S1386-6532(02)00045-8

Hepatitis C virus genotypes in Hungarian and Austrian patients with chronic hepatitis C

Zsófia Müller, Judith Deák, R. Stefan Ross, Elisabeth Nagy, László Kovács, M. Roggendorf, Harald H. Kessler

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Hepatitis C virus (HCV) genotypes are relevant to epidemiological questions, vaccine development, and clinical management of chronic HCV infection. The aim of this study was to determine HCV genotypes of South Hungarian and Southeast Austrian patients with chronic hepatitis C. Results were obtained by the largely automated TruGene HCV 5′NC Genotyping Kit (Visible Genetics, Toronto, Ontario) and by phylogenetic analysis. All of the 20 Hungarian patients and 15 out of 20 Austrian patients were infected with genotype 1. The remaining Austrian patients were infected with genotypes 3 or 2. With the commercially available assay, it was not possible to determine the HCV subtype in a total of three patients. The TruGene HCV 5′NC Genotyping assay for the determination of HCV genotypes proved to be useful for a high-throughput routine diagnostic laboratory.

Original language	English
Pages (from-to)	295-300
Number of pages	6
Journal	Journal of Clinical Virology
Volume	26
Issue number	3
DOIs	https://doi.org/10.1016/S1386-6532(02)00045-8
State	Published - Apr 2003
Externally published	Yes

Keywords

Austria
Genotype
HCV
Hungary
Sequencing

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S1386-6532(02)00045-8

Cite this

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title = "Hepatitis C virus genotypes in Hungarian and Austrian patients with chronic hepatitis C",

abstract = "Hepatitis C virus (HCV) genotypes are relevant to epidemiological questions, vaccine development, and clinical management of chronic HCV infection. The aim of this study was to determine HCV genotypes of South Hungarian and Southeast Austrian patients with chronic hepatitis C. Results were obtained by the largely automated TruGene HCV 5′NC Genotyping Kit (Visible Genetics, Toronto, Ontario) and by phylogenetic analysis. All of the 20 Hungarian patients and 15 out of 20 Austrian patients were infected with genotype 1. The remaining Austrian patients were infected with genotypes 3 or 2. With the commercially available assay, it was not possible to determine the HCV subtype in a total of three patients. The TruGene HCV 5′NC Genotyping assay for the determination of HCV genotypes proved to be useful for a high-throughput routine diagnostic laboratory.",

keywords = "Austria, Genotype, HCV, Hungary, Sequencing",

author = "Zs{\'o}fia M{\"u}ller and Judith De{\'a}k and Ross, {R. Stefan} and Elisabeth Nagy and L{\'a}szl{\'o} Kov{\'a}cs and M. Roggendorf and Kessler, {Harald H.}",

note = "Funding Information: This study was partly supported by the Scientific and Technological Cooperation between Austria and Hungary, project No. A-26/99.",

year = "2003",

month = apr,

doi = "10.1016/S1386-6532(02)00045-8",

language = "English",

volume = "26",

pages = "295--300",

journal = "Journal of Clinical Virology",

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TY - JOUR

T1 - Hepatitis C virus genotypes in Hungarian and Austrian patients with chronic hepatitis C

AU - Müller, Zsófia

AU - Deák, Judith

AU - Ross, R. Stefan

AU - Nagy, Elisabeth

AU - Kovács, László

AU - Roggendorf, M.

AU - Kessler, Harald H.

N1 - Funding Information: This study was partly supported by the Scientific and Technological Cooperation between Austria and Hungary, project No. A-26/99.

PY - 2003/4

Y1 - 2003/4

N2 - Hepatitis C virus (HCV) genotypes are relevant to epidemiological questions, vaccine development, and clinical management of chronic HCV infection. The aim of this study was to determine HCV genotypes of South Hungarian and Southeast Austrian patients with chronic hepatitis C. Results were obtained by the largely automated TruGene HCV 5′NC Genotyping Kit (Visible Genetics, Toronto, Ontario) and by phylogenetic analysis. All of the 20 Hungarian patients and 15 out of 20 Austrian patients were infected with genotype 1. The remaining Austrian patients were infected with genotypes 3 or 2. With the commercially available assay, it was not possible to determine the HCV subtype in a total of three patients. The TruGene HCV 5′NC Genotyping assay for the determination of HCV genotypes proved to be useful for a high-throughput routine diagnostic laboratory.

AB - Hepatitis C virus (HCV) genotypes are relevant to epidemiological questions, vaccine development, and clinical management of chronic HCV infection. The aim of this study was to determine HCV genotypes of South Hungarian and Southeast Austrian patients with chronic hepatitis C. Results were obtained by the largely automated TruGene HCV 5′NC Genotyping Kit (Visible Genetics, Toronto, Ontario) and by phylogenetic analysis. All of the 20 Hungarian patients and 15 out of 20 Austrian patients were infected with genotype 1. The remaining Austrian patients were infected with genotypes 3 or 2. With the commercially available assay, it was not possible to determine the HCV subtype in a total of three patients. The TruGene HCV 5′NC Genotyping assay for the determination of HCV genotypes proved to be useful for a high-throughput routine diagnostic laboratory.

KW - Austria

KW - Genotype

KW - HCV

KW - Hungary

KW - Sequencing

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U2 - 10.1016/S1386-6532(02)00045-8

DO - 10.1016/S1386-6532(02)00045-8

M3 - Article

C2 - 12637078

AN - SCOPUS:0347927332

SN - 1386-6532

VL - 26

SP - 295

EP - 300

JO - Journal of Clinical Virology

JF - Journal of Clinical Virology

IS - 3

ER -

Hepatitis C virus genotypes in Hungarian and Austrian patients with chronic hepatitis C

Abstract

Keywords

UN SDGs

Access to Document

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