HELFER-T-ZELLMANGEL BEI INFANTILER GENETISCHER AGRANULOZYTOSE (M. KOSTMANN)

K. G. Evers; S. E.G. Burdach; W. Ieromnimon; J. Kruger

HELFER-T-ZELLMANGEL BEI INFANTILER GENETISCHER AGRANULOZYTOSE (M. KOSTMANN)

Translated title of the contribution: Helper T-cell deficiency in congenital infantile genetic agranulocytosis (M. Kostmann)

K. G. Evers
, S. E.G. Burdach
, W. Ieromnimon
, J. Kruger

Kinderkrankenhaus der Stadt Köln

Research output: Contribution to journal › Article › peer-review

Abstract

A female Turkish infant with congenital infantile genetic agranulocytosis was examined for its distribution of lymphocyte subclasses. Imbalances of B cells and T-cell subpopulations were found. Compared to the normal control group a relative as well as an absolute deficiency of T helper cells and an increase of the absolute number of T suppressor cells were the most prominent findings. The importance of immunoregulatory T-cell subsets in the pathogenesis of infantile genetic agranulocytosis, disorders of hematopoiesis and granulocyte production, as well as primary and secondary immunodeficiencies is discussed.

Translated title of the contribution	Helper T-cell deficiency in congenital infantile genetic agranulocytosis (M. Kostmann)
Original language	German
Pages (from-to)	793-796
Number of pages	4
Journal	Monatsschrift fur Kinderheilkunde
Volume	131
Issue number	11
State	Published - 1983
Externally published	Yes

Cite this

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abstract = "A female Turkish infant with congenital infantile genetic agranulocytosis was examined for its distribution of lymphocyte subclasses. Imbalances of B cells and T-cell subpopulations were found. Compared to the normal control group a relative as well as an absolute deficiency of T helper cells and an increase of the absolute number of T suppressor cells were the most prominent findings. The importance of immunoregulatory T-cell subsets in the pathogenesis of infantile genetic agranulocytosis, disorders of hematopoiesis and granulocyte production, as well as primary and secondary immunodeficiencies is discussed.",

author = "Evers, \{K. G.\} and Burdach, \{S. E.G.\} and W. Ieromnimon and J. Kruger",

year = "1983",

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AU - Evers, K. G.

AU - Burdach, S. E.G.

AU - Ieromnimon, W.

AU - Kruger, J.

PY - 1983

Y1 - 1983

N2 - A female Turkish infant with congenital infantile genetic agranulocytosis was examined for its distribution of lymphocyte subclasses. Imbalances of B cells and T-cell subpopulations were found. Compared to the normal control group a relative as well as an absolute deficiency of T helper cells and an increase of the absolute number of T suppressor cells were the most prominent findings. The importance of immunoregulatory T-cell subsets in the pathogenesis of infantile genetic agranulocytosis, disorders of hematopoiesis and granulocyte production, as well as primary and secondary immunodeficiencies is discussed.

AB - A female Turkish infant with congenital infantile genetic agranulocytosis was examined for its distribution of lymphocyte subclasses. Imbalances of B cells and T-cell subpopulations were found. Compared to the normal control group a relative as well as an absolute deficiency of T helper cells and an increase of the absolute number of T suppressor cells were the most prominent findings. The importance of immunoregulatory T-cell subsets in the pathogenesis of infantile genetic agranulocytosis, disorders of hematopoiesis and granulocyte production, as well as primary and secondary immunodeficiencies is discussed.

UR - https://www.scopus.com/pages/publications/0021038268

M3 - Artikel

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AN - SCOPUS:0021038268

SN - 0026-9298

VL - 131

SP - 793

EP - 796

JO - Monatsschrift fur Kinderheilkunde

JF - Monatsschrift fur Kinderheilkunde

IS - 11

ER -

HELFER-T-ZELLMANGEL BEI INFANTILER GENETISCHER AGRANULOZYTOSE (M. KOSTMANN)

Abstract

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