Gut hormones ghrelin, PYY, and GLP-1 in the regulation of energy, balance, and metabolism

Diego Perez-Tilve; Ruben Nogueiras; Federico Mallo; Stephen C. Benoit; Matthias Tschoep

doi:10.1385/ENDO:29:1:61

Gut hormones ghrelin, PYY, and GLP-1 in the regulation of energy, balance, and metabolism

Diego Perez-Tilve
, Ruben Nogueiras
, Federico Mallo
, Stephen C. Benoit
, Matthias Tschoep

University of Cincinnati College of Medicine
German Institute of Human Nutrition
University of Vigo

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

The first hormone discovered in the gastrointestinal tract was secretin, isolated from duodenal mucosa. Some years later, two additional gastrointestinal hormones, gastrin and cholecystokinin (CCK), were discovered, but it was not until the 1970s that gastrointestinal endocrinology studies became more prevalent, resulting in the discovery of many more hormones. Here, we examine the role of gut hormones in energy balance regulation and their possible use as pharmaceutical targets for obesity.

Original language	English
Pages (from-to)	61-71
Number of pages	11
Journal	Endocrine
Volume	29
Issue number	1
DOIs	https://doi.org/10.1385/ENDO:29:1:61
State	Published - 2006
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

GLP-1
Gastrointestinal tract
Ghrelin
PYY

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10.1385/ENDO:29:1:61

Cite this

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abstract = "The first hormone discovered in the gastrointestinal tract was secretin, isolated from duodenal mucosa. Some years later, two additional gastrointestinal hormones, gastrin and cholecystokinin (CCK), were discovered, but it was not until the 1970s that gastrointestinal endocrinology studies became more prevalent, resulting in the discovery of many more hormones. Here, we examine the role of gut hormones in energy balance regulation and their possible use as pharmaceutical targets for obesity.",

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AU - Benoit, Stephen C.

AU - Tschoep, Matthias

PY - 2006

Y1 - 2006

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AB - The first hormone discovered in the gastrointestinal tract was secretin, isolated from duodenal mucosa. Some years later, two additional gastrointestinal hormones, gastrin and cholecystokinin (CCK), were discovered, but it was not until the 1970s that gastrointestinal endocrinology studies became more prevalent, resulting in the discovery of many more hormones. Here, we examine the role of gut hormones in energy balance regulation and their possible use as pharmaceutical targets for obesity.

KW - GLP-1

KW - Gastrointestinal tract

KW - Ghrelin

KW - PYY

UR - https://www.scopus.com/pages/publications/33646862588

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ER -

Gut hormones ghrelin, PYY, and GLP-1 in the regulation of energy, balance, and metabolism

Abstract

UN SDGs

Keywords

Access to Document

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