GTPases involved in vesicular trafficking: Structures and mechanisms

Aymelt Itzen, Roger S. Goody

Research output: Contribution to journalReview articlepeer-review

75 Scopus citations


Several types of GTPases play important roles in intracellular vesicular transport. These include the Rab and Arf families of the Ras superfamily, which are key regulators of several steps in the overall process. The basic structural and mechanistic properties of these proteins and their interactions with partner proteins and membranes are reviewed and compared in this article.

Original languageEnglish
Pages (from-to)48-56
Number of pages9
JournalSeminars in Cell and Developmental Biology
Issue number1
StatePublished - Feb 2011
Externally publishedYes


  • Arf
  • GTPases
  • Mechanism
  • Rab
  • Structure


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