GTPases involved in vesicular trafficking: Structures and mechanisms

Aymelt Itzen; Roger S. Goody

doi:10.1016/j.semcdb.2010.10.003

GTPases involved in vesicular trafficking: Structures and mechanisms

Aymelt Itzen, Roger S. Goody

Max Planck Inst. fur Molec. Physiol.

Research output: Contribution to journal › Review article › peer-review

76 Scopus citations

Abstract

Several types of GTPases play important roles in intracellular vesicular transport. These include the Rab and Arf families of the Ras superfamily, which are key regulators of several steps in the overall process. The basic structural and mechanistic properties of these proteins and their interactions with partner proteins and membranes are reviewed and compared in this article.

Original language	English
Pages (from-to)	48-56
Number of pages	9
Journal	Seminars in Cell and Developmental Biology
Volume	22
Issue number	1
DOIs	https://doi.org/10.1016/j.semcdb.2010.10.003
State	Published - Feb 2011
Externally published	Yes

Keywords

Arf
GTPases
Mechanism
Rab
Structure

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10.1016/j.semcdb.2010.10.003

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abstract = "Several types of GTPases play important roles in intracellular vesicular transport. These include the Rab and Arf families of the Ras superfamily, which are key regulators of several steps in the overall process. The basic structural and mechanistic properties of these proteins and their interactions with partner proteins and membranes are reviewed and compared in this article.",

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AB - Several types of GTPases play important roles in intracellular vesicular transport. These include the Rab and Arf families of the Ras superfamily, which are key regulators of several steps in the overall process. The basic structural and mechanistic properties of these proteins and their interactions with partner proteins and membranes are reviewed and compared in this article.

KW - Arf

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KW - Mechanism

KW - Rab

KW - Structure

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M3 - Review article

AN - SCOPUS:78751705518

SN - 1084-9521

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JO - Seminars in Cell and Developmental Biology

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GTPases involved in vesicular trafficking: Structures and mechanisms

Abstract

Keywords

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