Grip force control during object manipulation in cerebral stroke

J. Hermsdörfer, E. Hagl, D. A. Nowak, C. Marquardt

Research output: Contribution to journalArticlepeer-review

213 Scopus citations

Abstract

Objective: To analyze impairments of manipulative grip force control in patients with chronic cerebral stroke and relate deficits to more elementary aspects of force and grip control. Methods: Nineteen chronic stroke patients with fine motor deficits after unilateral cerebral lesions were examined when performing 3 manipulative tasks consisting of stationary holding, transport, and vertical cyclic movements of an instrumented object. Technical sensors measured the grip force used to stabilize the object in the hand and the object accelerations, from which the dynamic loads were calculated. Results: Many patients produced exaggerated grip forces with their affected hand in all types of manipulations. The amount of finger displacement in a grip perturbation task emerged as a highly sensitive measure for predicting the force increases. Measures of grip strength and maximum speed of force changes could not account for the impairments with comparable accuracy. In addition to force economy, the precision of the coupling between grip and load forces was impaired. However, no temporal delays were typically observed between the grip and load force profiles during cyclic movements. Conclusions: Impaired sensibility and sensorimotor processing, evident by delayed reactions in the perturbation task, lead to an excessive increase of the safety margin between the actual grip force and the minimum force necessary to prevent object slipping. In addition to grip force scaling, cortical sensorimotor areas are responsible for smoothly and precisely adjusting grip forces to loads according to predictions about movement-induced loads and sensory experiences. However, the basic feedforward mechanism of grip force control by internal models appears to be preserved, and thus may not be a cortical but rather a subcortical or cerebellar function, as has been suggested previously.

Original languageEnglish
Pages (from-to)915-929
Number of pages15
JournalClinical Neurophysiology
Volume114
Issue number5
DOIs
StatePublished - 1 May 2003
Externally publishedYes

Keywords

  • Fine motor deficits
  • Grip force control
  • Object manipulation
  • Sensorimotor integration
  • Stroke

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