@inproceedings{c5ae58f13a0c4fbda57a413ae8dd58f2,
title = "Grating-based tomography of human tissues",
abstract = "The development of therapies to improve our health requires a detailed knowledge on the anatomy of soft tissues from the human body down to the cellular level. Grating-based phase contrast micro computed tomography using synchrotron radiation provides a sensitivity, which allows visualizing micrometer size anatomical features in soft tissue without applying any contrast agent. We show phase contrast tomography data of human brain, tumor vessels and constricted arteries from the beamline ID 19 (ESRF) and urethral tissue from the beamline W2 (HASYLAB/DESY) with micrometer resolution. Here, we demonstrate that anatomical features can be identified within brain tissue as well known from histology. Using human urethral tissue, the application of two photon energies is compared. Tumor vessels thicker than 20 μm can be perfectly segmented. The morphology of coronary arteries can be better extracted in formalin than after paraffin embedding.",
keywords = "Thalamus, phase tomography, plaque, synchrotron radiation, tumor vessels, urethra",
author = "Bert M{\"u}ller and Georg Schulz and Andrea Mehlin and Julia Herzen and Sabrina Lang and Margaret Holme and Irene Zanette and Simone Hieber and Hans Deyhle and Felix Beckmann and Franz Pfeiffer and Timm Weitkamp",
year = "2012",
doi = "10.1063/1.4742277",
language = "English",
isbn = "9780735410725",
series = "AIP Conference Proceedings",
pages = "107--112",
booktitle = "International Workshop on X-Ray and Neutron Phase Imaging with Gratings",
note = "International Workshop on X-Ray and Neutron Phase Imaging with Gratings, XNPIG 2012 ; Conference date: 05-03-2012 Through 07-03-2012",
}