Gold finger formation studied by high-resolution mass spectrometry and in silico methods

A. Laskay, C. Garino, Y. O. Tsybin, L. Salassa, A. Casini

Research output: Contribution to journalArticlepeer-review

35 Scopus citations

Abstract

High-resolution mass spectrometry and quantum mechanics/molecular mechanics studies were employed for characterizing the formation of two gold finger (GF) domains from the reaction of zinc fingers (ZF) with gold complexes. The influence of both the gold oxidation state and the ZF coordination sphere in GF formation provided useful insights into the possible design of new gold complexes targeting specific ZF motifs.

Original languageEnglish
Pages (from-to)1612-1615
Number of pages4
JournalChemical Communications
Volume51
Issue number9
DOIs
StatePublished - 31 Jan 2015
Externally publishedYes

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