TY - JOUR
T1 - Glycosyltransferases
T2 - Managers of small molecules
AU - Bowles, Dianna
AU - Isayenkova, Judith
AU - Lim, Eng Kiat
AU - Poppenberger, Brigitte
N1 - Funding Information:
Support is gratefully acknowledged from The Garfield Weston Foundation, the UK Biotechnology and Biological Sciences Research Council (BBSRC) and the Austrian Science Fund FWF (BP is the recipient of an Erwin-Schroedinger fellowship). Japan Fresh Fruits, Shu Suehiro and Noriko Hamakko are thanked for allowing us to use photographs. Current members of the laboratory, Adam Cartwright, Luisa Elias, Gilu George, Bingkai Hou, Alexandra Lanot, David Priest, Fabián Vaistij and Markus Weis are thanked for their sense of humour and support.
PY - 2005/6
Y1 - 2005/6
N2 - Studies of the glycosyltransferases (GTs) of small molecules have greatly increased in recent years as new approaches have been used to identify their genes and characterize their catalytic activities. These enzymes recognize diverse acceptors, including plant metabolites, phytotoxins and xenobiotics. Glycosylation alters the hydrophilicity of the acceptors, their stability and chemical properties, their subcellular localisation and often their bioactivity. Considerable progress has been made in understanding the role of GTs in the plant and the utility of GTs as biocatalysts, the latter arising from their regio- and enantioselectivity and their ability to recognize substrates that are not limited to plant metabolites.
AB - Studies of the glycosyltransferases (GTs) of small molecules have greatly increased in recent years as new approaches have been used to identify their genes and characterize their catalytic activities. These enzymes recognize diverse acceptors, including plant metabolites, phytotoxins and xenobiotics. Glycosylation alters the hydrophilicity of the acceptors, their stability and chemical properties, their subcellular localisation and often their bioactivity. Considerable progress has been made in understanding the role of GTs in the plant and the utility of GTs as biocatalysts, the latter arising from their regio- and enantioselectivity and their ability to recognize substrates that are not limited to plant metabolites.
UR - http://www.scopus.com/inward/record.url?scp=18144379937&partnerID=8YFLogxK
U2 - 10.1016/j.pbi.2005.03.007
DO - 10.1016/j.pbi.2005.03.007
M3 - Review article
C2 - 15860422
AN - SCOPUS:18144379937
SN - 1369-5266
VL - 8
SP - 254
EP - 263
JO - Current Opinion in Plant Biology
JF - Current Opinion in Plant Biology
IS - 3 SPEC. ISS.
ER -