Glycogen storage disease type Ib: Infectious complications and measures for prevention

U. Wendel, H. Schroten, S. Burdach, V. Wahn

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

A patient with glycogen storage disease (GSD) type Ib, neutrophenia, chronic inflammatory bowel disease and recurrent abscesses was treated with recombinant human granulocyte-macrophage colony stimulating factor (GM-CSF). GM-CSF (and also granulocyte colony stimulating factor) therapy markedly increased the neutrophil counts and reduced the frequency of infections and inflammation. We conclude that myeloid growth factors are effective for the treatment and prevention of acute infections and chronic inflammatory complications in patients with GSD Ib.

Original languageEnglish
Pages (from-to)49-51
Number of pages3
JournalEuropean Journal of Pediatrics
Volume152
Issue number1 Supplement
DOIs
StatePublished - Jan 1993
Externally publishedYes

Keywords

  • Crohn-like disease
  • Glycogen storage disease type Ib
  • Granulocyte-macrophage colony stimulating factor treatment
  • Neutropenia

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