Keyphrases
Autophagy
100%
Innate Immune Response
100%
Genotoxic Stress
100%
CGAS-STING
100%
Trisomic
100%
Transcription Factor
40%
Human Cells
40%
Nuclear Localization
40%
Extra Chromosomes
40%
Inflammatory Response
20%
Molecular Mechanism
20%
Lysosomal Degradation
20%
Lysosomal Genes
20%
Cellular Physiology
20%
Embryonic Fibroblasts
20%
Signaling Cascades
20%
Stimulator of Interferon Genes (STING)
20%
DNA Replication
20%
Single-stranded DNA (ssDNA)
20%
Type I Interferon Response
20%
Cellular Processes
20%
Constitutive Activation
20%
Aneuploidy
20%
MTORC1 Signaling
20%
Down Syndrome
20%
Associated Pathologies
20%
Nuclear Accumulation
20%
Autophagy-related Genes
20%
Single Chromosome
20%
Upstream Regulator
20%
Cyclic GMP-AMP Synthase (cGAS)
20%
Interferon Regulatory Factor 3 (IRF3)
20%
STING Activation
20%
Autophagy Response
20%
Biochemistry, Genetics and Molecular Biology
Trisomy
100%
Innate Immunity
100%
Autophagy
100%
TFEB
50%
Upregulation
50%
Transcription Factors
33%
Interferon-Stimulated Gene
16%
Aneuploidy
16%
Cell Function
16%
down Regulation
16%
Interferon Type I
16%
IRF3
16%
Supernumerary Chromosome
16%
DNA Synthesis
16%
Down Syndrome
16%
Fibroblast
16%
Immunology and Microbiology
Innate Immune System
100%
Autophagy
100%
Upregulation
50%
Transcription Factors
33%
Interferon Type I
16%
Inflammation Response
16%
Human Cell
16%
Cell Function
16%
down Regulation
16%
Interferon-Stimulated Gene
16%
IRF3
16%
Supernumerary Chromosome
16%
DNA Synthesis
16%
Fibroblast
16%