Genomic alterations and allelic imbalances are strong prognostic predictors in osteosarcoma

Keyphrases

• 6p21 20%
• 8q24 20%
• Aberrations 20%
• Adverse Outcomes 20%
• Affymetrix 20%
• Allelic Imbalance 100%
• Biopsy Specimen 20%
• Chromosome Rearrangement 60%
• Clinical Course 20%
• Clinical Follow-up 40%
• Complex Karyotype 20%
• Copy number Variation 20%
• Cyclin-dependent Kinase 4 (CDK4) 20%
• Delayed Diagnosis 20%
• Genetic Modification 100%
• Heterozygosity 20%
• High Density 20%
• Histologic Evaluation 20%
• Histological Regression 20%
• Initial Diagnosis 20%
• Loss of Heterozygosity 40%
• Molecular Prognostic Marker 20%
• Necrosis 20%
• Neoadjuvant Chemotherapy 20%
• Neoadjuvant Therapy 20%
• Numerical Aberrations 20%
• Osteosarcoma 100%
• Predictive Factors 20%
• Predictive Potential 20%
• Primary Malignant Tumors 20%
• Prognostic Factors 100%
• Prognostic Impact 20%
• Regression Grading 20%
• Response to Chemotherapy 20%
• Single nucleotide Polymorphism Analysis 20%
• SNP Array 20%
• Staging System 40%
• Therapeutic Impact 20%
• Total Degree 20%
• Tumor 20%

Biochemistry, Genetics and Molecular Biology

• Allelic Imbalance 100%
• Copy-Number Variation 50%
• Genomics 100%
• Heterozygosity 50%
• Karyotype 50%
• Loss of Heterozygosity 100%
• Single-Nucleotide Polymorphism 100%