@article{0869eb1ba3ef4b1b9144ec1cb940486d,
title = "Genome-wide association studies of atrial fibrillation: Past, present, and future",
abstract = "Genome-wide association studies (GWAS) for atrial fibrillation (AF) have identified three distinct genetic loci on chromosomes 1q21, 4q25, and 16q22 that are associated with the arrhythmia. Susceptibility loci also have been identified by GWAS for PR interval duration, a quantitative phenotype related to AF. In this review article, we have sought to summarize the latest findings for population-based genetic studies of AF, to highlight ongoing functional studies, and to explore the future directions of genetic research on AF. Published on behalf of the European Society of Cardiology. All rights reserved.",
keywords = "Arrhythmia, Atrial fibrillation, Genetics, Genome-wide association study, Single nucleotide polymorphism",
author = "Sinner, {Moritz F.} and Ellinor, {Patrick T.} and Thomas Meitinger and Benjamin, {Emelia J.} and Stefan K{\"a}{\"a}b",
note = "Funding Information: This work was supported by the National Institutes of Health (1R01HL092577 to E.J.B. and P.T.E.; 1RC1HL101056, 1R01HL102214 to E.J.B; 1R01HL104156, 5R21DA027021, 1K24HL105780 to P.T.E.); Bundesministerium f{\"u}r Bildung und Forschung BMBF (German Competence Network on AF AFNET 01 GI 0204/N, German National Genome Research Network NGFN 01GS0499, 01GS0838 to S.K.; Leducq Foundation (07-CVD 03 to E.J.B., P.T.E. and S.K.); LMU Excellence Initiative to S.K.; LMU Research grant (F{\"o}FoLe 557/569 to M.F.S.). M.F.S. is supported by the German Heart Foundation.",
year = "2011",
month = mar,
day = "1",
doi = "10.1093/cvr/cvr001",
language = "English",
volume = "89",
pages = "701--709",
journal = "Cardiovascular Research",
issn = "0008-6363",
publisher = "Oxford University Press",
number = "4",
}