Genome-based structural biology

Dmitrij Frishman, Hans Werner Mewes

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Spectacular achievements in whole genome sequencing open up new possibilities for structural research. Protein structures can now be studied in their natural genomic context. On the other hand, structure prediction algorithms can be improved using species-specific tendencies in folding patterns. Finally, efficient strategies to select targets for structure determination can be devised. In this review we consider new computational approaches and results in protein structure analysis stemming from the availability of complete genomes.

Original languageEnglish
Pages (from-to)1-17
Number of pages17
JournalProgress in Biophysics and Molecular Biology
Issue number1
StatePublished - Jun 1999
Externally publishedYes


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