Genistein and dicarboximide fungicides in infant formulae from the EU market

Silvia Maggioni; Renzo Bagnati; Marchela Pandelova; Karl Werner Schramm; Emilio Benfenati

doi:10.1016/j.foodchem.2012.07.094

Genistein and dicarboximide fungicides in infant formulae from the EU market

Silvia Maggioni, Renzo Bagnati, Marchela Pandelova, Karl Werner Schramm, Emilio Benfenati

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

A method based on ultrasonic extraction and purification by solid phase extraction followed by LC-MS/MS and GC-MS analysis was developed for the determination of genistein, genistin, iprodione, vinclozolin and procymidone in infant powdered formulas. The method was tested for different formulations: milk, soy and hypoallergenic, and was applied to European pooled samples. Spike recoveries ranged from 53.1% to 91.5% and the relative standard deviation values for repeatability ranged from 9.6% to 17.7%, except for iprodione in milk formula (22.3%). None of the fungicides were found in the European pooled formulae, while genistein was found at 9.7 μg/g in soy formula and the concentration of genistin, its β-glycosylated form, was respectively 31.4 ng/g and 476 ng/g in milk and soy formula.

Original language	English
Pages (from-to)	116-119
Number of pages	4
Journal	Food Chemistry
Volume	136
Issue number	1
DOIs	https://doi.org/10.1016/j.foodchem.2012.07.094
State	Published - 1 Jan 2013
Externally published	Yes

Keywords

Fungicide
GC-MS
Infant formula
Isoflavone
LC-MS/MS
Phytoestrogen

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10.1016/j.foodchem.2012.07.094

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title = "Genistein and dicarboximide fungicides in infant formulae from the EU market",

abstract = "A method based on ultrasonic extraction and purification by solid phase extraction followed by LC-MS/MS and GC-MS analysis was developed for the determination of genistein, genistin, iprodione, vinclozolin and procymidone in infant powdered formulas. The method was tested for different formulations: milk, soy and hypoallergenic, and was applied to European pooled samples. Spike recoveries ranged from 53.1% to 91.5% and the relative standard deviation values for repeatability ranged from 9.6% to 17.7%, except for iprodione in milk formula (22.3%). None of the fungicides were found in the European pooled formulae, while genistein was found at 9.7 μg/g in soy formula and the concentration of genistin, its β-glycosylated form, was respectively 31.4 ng/g and 476 ng/g in milk and soy formula.",

keywords = "Fungicide, GC-MS, Infant formula, Isoflavone, LC-MS/MS, Phytoestrogen",

author = "Silvia Maggioni and Renzo Bagnati and Marchela Pandelova and Schramm, {Karl Werner} and Emilio Benfenati",

note = "Funding Information: This work was funded by the EC within the project CASCADE NoE (Chemicals as contaminants in the food chain: an Network of Excellence for research, risk assessment and education. Project Reference: 506319. Action Line: FOOD-2002-T41 Human health implications of exposure to chemical residues in the environment http://cordis.europa.eu/projects/rcn/74150_en.html accessed June 2012). Funding Information: The first author{\textquoteright}s research fellowship was funded by Rotary Club Milano.",

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AU - Benfenati, Emilio

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Genistein and dicarboximide fungicides in infant formulae from the EU market

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Keywords

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