TY - JOUR
T1 - Genetically Encoded Oligomerization for Protein-Based Lighting Devices
AU - Patrian, Marta
AU - Nieddu, Mattia
AU - Banda-Vázquez, Jesús A.
AU - Gutierrez-Armayor, David
AU - González-Gaitano, Gustavo
AU - Fuenzalida-Werner, Juan Pablo
AU - Costa, Rubén D.
N1 - Publisher Copyright:
© 2023 The Authors. Advanced Materials published by Wiley-VCH GmbH.
PY - 2023/11/28
Y1 - 2023/11/28
N2 - Implementing proteins in optoelectronics represents a fresh idea toward a sustainable new class of materials with bio-functions that can replace environmentally unfriendly and/or toxic components without losing device performance. However, their native activity (fluorescence, catalysis, and so on) is easily lost under device fabrication/operation as non-native environments (organic solvents, organic/inorganic interfaces, and so on) and severe stress (temperature, irradiation, and so on) are involved. Herein, a gift bow genetically-encoded macro-oligomerization strategy is showcased to promote protein–protein solid interaction enabling i) high versatility with arbitrary proteins, ii) straightforward electrostatic driven control of the macro-oligomer size by ionic strength, and iii) stabilities over months in pure organic solvents and stress scenarios, allowing to integrate them into classical water-free polymer-based materials/components for optoelectronics. Indeed, rainbow-/white-emitting protein-based light-emitting diodes are fabricated, attesting a first-class performance compared to those with their respective native proteins: significantly enhanced device stabilities from a few minutes up to 100 h keeping device efficiency at high power driving conditions. Thus, the oligomerization concept is a solid bridge between biological systems and materials/components to meet expectations in bio-optoelectronics, in general, and lighting schemes, in particular.
AB - Implementing proteins in optoelectronics represents a fresh idea toward a sustainable new class of materials with bio-functions that can replace environmentally unfriendly and/or toxic components without losing device performance. However, their native activity (fluorescence, catalysis, and so on) is easily lost under device fabrication/operation as non-native environments (organic solvents, organic/inorganic interfaces, and so on) and severe stress (temperature, irradiation, and so on) are involved. Herein, a gift bow genetically-encoded macro-oligomerization strategy is showcased to promote protein–protein solid interaction enabling i) high versatility with arbitrary proteins, ii) straightforward electrostatic driven control of the macro-oligomer size by ionic strength, and iii) stabilities over months in pure organic solvents and stress scenarios, allowing to integrate them into classical water-free polymer-based materials/components for optoelectronics. Indeed, rainbow-/white-emitting protein-based light-emitting diodes are fabricated, attesting a first-class performance compared to those with their respective native proteins: significantly enhanced device stabilities from a few minutes up to 100 h keeping device efficiency at high power driving conditions. Thus, the oligomerization concept is a solid bridge between biological systems and materials/components to meet expectations in bio-optoelectronics, in general, and lighting schemes, in particular.
KW - bio-hybrid light-emitting diodes
KW - engineered fluorescent proteins
KW - oligomerization
KW - organic solvent stability
KW - protein-based lighting
UR - http://www.scopus.com/inward/record.url?scp=85174285772&partnerID=8YFLogxK
U2 - 10.1002/adma.202303993
DO - 10.1002/adma.202303993
M3 - Article
AN - SCOPUS:85174285772
SN - 0935-9648
VL - 35
JO - Advanced Materials
JF - Advanced Materials
IS - 48
M1 - 2303993
ER -