General and selective iron-catalyzed transfer hydrogenation of nitroarenes without base

Gerrit Wienhöfer, Iván Sorribes, Albert Boddien, Felix Westerhaus, Kathrin Junge, Henrik Junge, Rosa Llusar, Matthias Beller

Research output: Contribution to journalArticlepeer-review

317 Scopus citations

Abstract

The first well-defined iron-based catalyst system for the reduction of nitroarenes to anilines has been developed applying formic acid as reducing agent. A broad range of substrates including other reducible functional groups were converted to the corresponding anilines in good to excellent yields at mild conditions. Notably, the process constitutes a rare example of base-free transfer hydrogenations.

Original languageEnglish
Pages (from-to)12875-12879
Number of pages5
JournalJournal of the American Chemical Society
Volume133
Issue number32
DOIs
StatePublished - 17 Aug 2011
Externally publishedYes

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