TY - JOUR
T1 - Gastrointestinal signalling peptides in obesity
AU - Nogueiras, Ruben
AU - Caton, Samantha J.
AU - Perez-Tilve, Diego
AU - Bidlingmaier, Martin
AU - Tschöp, Matthias H.
PY - 2006
Y1 - 2006
N2 - Numerous peptides are synthesized and released from distinct populations of specific secretory cells throughout the gastrointestinal tract. Their roles in the regulation of gastrointestinal function have been well known for many years, but it is now evident that they also modulate orexigenic drive and energy metabolism via different mechanisms. Thereby, these peptides represent potential targets for the design of anti-obesity drugs. In this review, we summarize the main gastrointestinal peptides and their physiological functions.
AB - Numerous peptides are synthesized and released from distinct populations of specific secretory cells throughout the gastrointestinal tract. Their roles in the regulation of gastrointestinal function have been well known for many years, but it is now evident that they also modulate orexigenic drive and energy metabolism via different mechanisms. Thereby, these peptides represent potential targets for the design of anti-obesity drugs. In this review, we summarize the main gastrointestinal peptides and their physiological functions.
UR - http://www.scopus.com/inward/record.url?scp=33847008766&partnerID=8YFLogxK
U2 - 10.1016/j.ddmec.2006.11.013
DO - 10.1016/j.ddmec.2006.11.013
M3 - Review article
AN - SCOPUS:33847008766
SN - 1740-6765
VL - 3
SP - 463
EP - 470
JO - Drug Discovery Today: Disease Mechanisms
JF - Drug Discovery Today: Disease Mechanisms
IS - 4
ER -
