Gastrointestinal involvement in patients with diabetes mellitus: Part II (second of two parts) - Diagnostic procedures, pharmacological and nonpharmacological therapy

C. Folwaczny, R. Riepl, M. Tschöp, R. Landgraf

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Diagnostic work-up in patients with diabetes mellitus, in whom gastrointestinal involvement is suspected comprises the assessment of gastrointestinal transit times, endoscopy, esophageal pH-metry or manometry, sonography and lactulose- or glucose-H2-breath tests. Prokinetic agents such as metoclopramide, cisapride or erythromycin and substances like loperamide, octreotide or clonidine are used to improve gastrointestinal dysfunction. Furthermore, in recent trials which aimed for the modulation of gastrointestinal transit times, cholecystokinin, proteinase inhibitors or amylin were administered in patients with diabetes mellitus. Nonpharmacological interventions include pancreas and kidney transplantation, gastric pacemakers and biofeedback training.

Original languageEnglish
Pages (from-to)817-826
Number of pages10
JournalZeitschrift fur Gastroenterologie
Volume37
Issue number9
StatePublished - Sep 1999

Keywords

  • Amylin
  • Cholecystokinin
  • Cisapride
  • Erythromycin
  • Glucagon-like peptide
  • Octreotide
  • Prokinetic drugs
  • Proteinase inhibitor II

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