TY - JOUR
T1 - Gastrointestinal involvement in patients with diabetes mellitus
T2 - Part II (second of two parts) - Diagnostic procedures, pharmacological and nonpharmacological therapy
AU - Folwaczny, C.
AU - Riepl, R.
AU - Tschöp, M.
AU - Landgraf, R.
PY - 1999/9
Y1 - 1999/9
N2 - Diagnostic work-up in patients with diabetes mellitus, in whom gastrointestinal involvement is suspected comprises the assessment of gastrointestinal transit times, endoscopy, esophageal pH-metry or manometry, sonography and lactulose- or glucose-H2-breath tests. Prokinetic agents such as metoclopramide, cisapride or erythromycin and substances like loperamide, octreotide or clonidine are used to improve gastrointestinal dysfunction. Furthermore, in recent trials which aimed for the modulation of gastrointestinal transit times, cholecystokinin, proteinase inhibitors or amylin were administered in patients with diabetes mellitus. Nonpharmacological interventions include pancreas and kidney transplantation, gastric pacemakers and biofeedback training.
AB - Diagnostic work-up in patients with diabetes mellitus, in whom gastrointestinal involvement is suspected comprises the assessment of gastrointestinal transit times, endoscopy, esophageal pH-metry or manometry, sonography and lactulose- or glucose-H2-breath tests. Prokinetic agents such as metoclopramide, cisapride or erythromycin and substances like loperamide, octreotide or clonidine are used to improve gastrointestinal dysfunction. Furthermore, in recent trials which aimed for the modulation of gastrointestinal transit times, cholecystokinin, proteinase inhibitors or amylin were administered in patients with diabetes mellitus. Nonpharmacological interventions include pancreas and kidney transplantation, gastric pacemakers and biofeedback training.
KW - Amylin
KW - Cholecystokinin
KW - Cisapride
KW - Erythromycin
KW - Glucagon-like peptide
KW - Octreotide
KW - Prokinetic drugs
KW - Proteinase inhibitor II
UR - http://www.scopus.com/inward/record.url?scp=0032863366&partnerID=8YFLogxK
M3 - Article
C2 - 10522368
AN - SCOPUS:0032863366
SN - 0044-2771
VL - 37
SP - 817
EP - 826
JO - Zeitschrift fur Gastroenterologie
JF - Zeitschrift fur Gastroenterologie
IS - 9
ER -