Full-view low-cost LED-based optoacoustic tomography

Xiang Liu, Sandeep Kumar Kalva, Berkan Lafci, Daniil Nozdriukhin, Xosé Luís Deán-Ben, Daniel Razansky

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Optoacoustic tomography is typically implemented with bulky solid-state lasers delivering per-pulse energies in the millijoule range. Light emitting diodes (LEDs) represent a cost-effective and portable alternative for signal excitation further offering excellent pulse-to-pulse stability. Herein, we describe a full-view LED-based optoacoustic tomography (FLOAT) system for deep-tissue in vivo imaging. A custom-made electronic unit driving a stacked array of LEDs attains stable light pulses with total per-pulse energy of 0.48 mJ and 100 ns pulse width. The LED array was arranged on a circular configuration and integrated in a full-ring ultrasound array enabling full-view tomographic imaging performance in cross-sectional (2D) geometry. As a proof of concept, we scanned the medial phalanx of the index finger without extrinsic administration of a contrast agent. We anticipate that this compact, affordable, and versatile illumination technology will facilitate dissemination of the optoacoustic technology in resource-limited settings.

Original languageEnglish
Title of host publicationPhotons Plus Ultrasound
Subtitle of host publicationImaging and Sensing 2024
EditorsAlexander A. Oraevsky, Lihong V. Wang
PublisherSPIE
ISBN (Electronic)9781510669437
DOIs
StatePublished - 2024
Externally publishedYes
EventPhotons Plus Ultrasound: Imaging and Sensing 2024 - San Francisco, United States
Duration: 28 Jan 202431 Jan 2024

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume12842
ISSN (Print)1605-7422

Conference

ConferencePhotons Plus Ultrasound: Imaging and Sensing 2024
Country/TerritoryUnited States
CitySan Francisco
Period28/01/2431/01/24

Keywords

  • LED
  • circular array transducer
  • full view
  • low-cost light sources
  • optoacoustic/photoacoustic tomography

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