From noble metal to Nobel Prize: Palladium-catalyzed coupling reactions as key methods in organic synthesis

Xiao Feng Wu, Pazhamalai Anbarasan, Helfried Neumann, Matthias Beller

Research output: Contribution to journalArticlepeer-review

532 Scopus citations

Abstract

Building bridges: Palladium-catalyzed cross-coupling reactions of aryl halides and related compounds allow the expeditious and controlled synthesis of important carbon-based scaffolds (see scheme). Their essential role in organic chemistry has resulted in such reactions being recognized by the Nobel Prize for Chemistry 2010.

Original languageEnglish
Pages (from-to)9047-9050
Number of pages4
JournalAngewandte Chemie International Edition in English
Volume49
Issue number48
DOIs
StatePublished - 22 Nov 2010
Externally publishedYes

Keywords

  • Heck reaction
  • Negishi coupling
  • Suzuki coupling
  • cross-coupling
  • palladium

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