TY - GEN
T1 - Freehand tomographic nuclear imaging using tracked high-energy gamma probes
AU - Okur, Asli
AU - Shakir, Dzhoshkun I.
AU - Matthies, Philipp
AU - Hartl, Alexander
AU - Ziegler, Sibylle I.
AU - Essler, Markus
AU - Lasser, Tobias
AU - Navab, Nassir
N1 - Publisher Copyright:
© Springer-Verlag Berlin Heidelberg 2013.
PY - 2013
Y1 - 2013
N2 - Systems allowing freehand SPECT imaging inside the operating room have been introduced previously. In this work, we aim to take one step further and enable 3D freehand imaging using positron emitting radio-traces such as [18F]FDG. Our system combines a high-energy gamma probe with an optical tracking system. Detection of the 511keV annihilation gammas from positron-emitting radio-tracers is modeled analytically. The algorithm iteratively reconstructs the radioactivity distribution within a localized volume of interest. Based on the PET/CT data of 7 patients with tumors and lymph node metastases in the head and neck region, we build a neck phantom with [18F]FDG-filled reservoirs representing tumors and lymph nodes. Using this phantom, we investigate the limitations and capabilities of our method. Finally, we discuss possible improvements and requirements needed so that our approach becomes clinically applicable.
AB - Systems allowing freehand SPECT imaging inside the operating room have been introduced previously. In this work, we aim to take one step further and enable 3D freehand imaging using positron emitting radio-traces such as [18F]FDG. Our system combines a high-energy gamma probe with an optical tracking system. Detection of the 511keV annihilation gammas from positron-emitting radio-tracers is modeled analytically. The algorithm iteratively reconstructs the radioactivity distribution within a localized volume of interest. Based on the PET/CT data of 7 patients with tumors and lymph node metastases in the head and neck region, we build a neck phantom with [18F]FDG-filled reservoirs representing tumors and lymph nodes. Using this phantom, we investigate the limitations and capabilities of our method. Finally, we discuss possible improvements and requirements needed so that our approach becomes clinically applicable.
UR - https://www.scopus.com/pages/publications/84923798760
U2 - 10.1007/978-3-642-36480-8_63
DO - 10.1007/978-3-642-36480-8_63
M3 - Conference contribution
AN - SCOPUS:84923798760
T3 - Informatik aktuell
SP - 362
EP - 367
BT - Bildverarbeitung fur die Medizin 2013
A2 - Meinzer, Hans-Peter
A2 - Deserno, Thomas Martin
A2 - Handels, Heinz
A2 - Tolxdorff, Thomas
PB - Kluwer Academic Publishers
T2 - Workshops Bildverarbeitung fur die Medizin: Algorithmen - Systeme - Anwendungen, BVM 2013 - Workshop on Image Processing for Medicine: Algorithms - Systems - Applications, BVM 2013
Y2 - 3 March 2013 through 5 March 2013
ER -