TY - JOUR
T1 - Früherkennung von Typ-1-Diabetes durch Inselautoantikörper-Screening - ein Positionspapier der Fr1da Plex -Projektleiter und -Schulungszentren, des BVKJ Bayern und PaedNetz Bayern eV.
AU - Achenbach, Peter
AU - Berner, Reinhard
AU - Bonifacio, Ezio
AU - Brämswig, Susanne
AU - Braig, Sonja
AU - Dunstheimer, Desiree
AU - Ermer, Uwe
AU - Ewald, Dominik
AU - Gemulla, Gita
AU - Hauer, Julia
AU - Haupt, Florian
AU - Haus, Gabi
AU - Hubmann, Michael
AU - Hummel, Sandra
AU - Kandler, Michael
AU - Kordonouri, Olga
AU - Lange, Karin
AU - Laub, Otto
AU - Lorrmann, Anja
AU - Nellen-Hellmuth, Nicole
AU - Sindichakis, Marina
AU - Von Dem Berge, Thekla
AU - Warncke, Katharina
AU - Weber, Leonie
AU - Winkler, Christiane
AU - Wintermeyer, Philip
AU - Ziegler, Anette Gabriele
N1 - Publisher Copyright:
© 2023 Georg Thieme Verlag. All rights reserved.
PY - 2023
Y1 - 2023
N2 - This position paper is based on the authors' many years of clinical experience and basic science research on the diagnosis and treatment of children and adolescents with a presymptomatic early stage of type 1 diabetes. The benefits as well as potential disadvantages of early detection of type 1 diabetes by islet autoantibody screening are critically discussed. In addition, the perspectives of delaying the onset of the clinical metabolic disease through treatment with teplizumab are addressed. Today, we see the chance of a relevant improvement in the therapeutic options and life perspectives of affected children and adolescents. Important next steps for the implementation of islet autoantibody screening in Germany are the training of pediatricians who should inform families about the screening, the establishment of a few transregional laboratories that carry out the test, and the expansion of regional capacities for the training and care of children with an early stage of type 1 diabetes.
AB - This position paper is based on the authors' many years of clinical experience and basic science research on the diagnosis and treatment of children and adolescents with a presymptomatic early stage of type 1 diabetes. The benefits as well as potential disadvantages of early detection of type 1 diabetes by islet autoantibody screening are critically discussed. In addition, the perspectives of delaying the onset of the clinical metabolic disease through treatment with teplizumab are addressed. Today, we see the chance of a relevant improvement in the therapeutic options and life perspectives of affected children and adolescents. Important next steps for the implementation of islet autoantibody screening in Germany are the training of pediatricians who should inform families about the screening, the establishment of a few transregional laboratories that carry out the test, and the expansion of regional capacities for the training and care of children with an early stage of type 1 diabetes.
UR - http://www.scopus.com/inward/record.url?scp=85193536922&partnerID=8YFLogxK
U2 - 10.1055/a-2320-2859
DO - 10.1055/a-2320-2859
M3 - Artikel
AN - SCOPUS:85193536922
SN - 0941-3790
JO - Gesundheitswesen
JF - Gesundheitswesen
ER -