Abstract
Just recently, new diagnostic criteria for Alzheimer's disease (AD) allow the diagnosis of the disease solely on biomarkers independently from the clinical syndrome. In particular, biomarkers for Amyloid pathology already become abnormal many years before symptom onset. In addition, if biomarkers for Tau and neurodegeneration turn positive, diagnostic specificity and probability deterioration increases substantially. The usefulness of the AD biomarkers for early detection and prognosis will be discussed. AD biomarkers allow the detection of AD already at the pre-dementia level. This offers the opportunity to identify candidates for disease-modifying treatment options.
| Translated title of the contribution | Early detection of Alzheimer's Disease using imaging or cerebro-spinal fluid biomarkers |
|---|---|
| Original language | German |
| Pages (from-to) | 813-816 |
| Number of pages | 4 |
| Journal | Nervenheilkunde |
| Volume | 38 |
| Issue number | 11 |
| DOIs | |
| State | Published - 2019 |