FoxP3 forkhead dimer: Don't swap me now

Indra Bekere; Carina C. de Oliveira Mann

doi:10.1016/j.immuni.2022.07.012

FoxP3 forkhead dimer: Don't swap me now

Indra Bekere, Carina C. de Oliveira Mann

Assistant Professorship of Biomolecular Cryo-Electron Microscopy

Technical University of Munich

Research output: Contribution to journal › Comment/debate

Abstract

FoxP3 is critical for regulatory T cell function and, thus, overall immune homeostasis. In this issue of Immunity, Leng et al. reveal how FoxP3 achieves specific recognition of DNA and functional specialization by adopting a head-to-head domain conformation.

Original language	English
Pages (from-to)	1329-1331
Number of pages	3
Journal	Immunity
Volume	55
Issue number	8
DOIs	https://doi.org/10.1016/j.immuni.2022.07.012
State	Published - 9 Aug 2022

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10.1016/j.immuni.2022.07.012

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title = "FoxP3 forkhead dimer: Don't swap me now",

abstract = "FoxP3 is critical for regulatory T cell function and, thus, overall immune homeostasis. In this issue of Immunity, Leng et al. reveal how FoxP3 achieves specific recognition of DNA and functional specialization by adopting a head-to-head domain conformation.",

author = "Indra Bekere and \{de Oliveira Mann\}, \{Carina C.\}",

note = "Publisher Copyright: {\textcopyright} 2022 Elsevier Inc.",

year = "2022",

month = aug,

day = "9",

doi = "10.1016/j.immuni.2022.07.012",

language = "English",

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T1 - FoxP3 forkhead dimer

T2 - Don't swap me now

AU - Bekere, Indra

AU - de Oliveira Mann, Carina C.

PY - 2022/8/9

Y1 - 2022/8/9

N2 - FoxP3 is critical for regulatory T cell function and, thus, overall immune homeostasis. In this issue of Immunity, Leng et al. reveal how FoxP3 achieves specific recognition of DNA and functional specialization by adopting a head-to-head domain conformation.

AB - FoxP3 is critical for regulatory T cell function and, thus, overall immune homeostasis. In this issue of Immunity, Leng et al. reveal how FoxP3 achieves specific recognition of DNA and functional specialization by adopting a head-to-head domain conformation.

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U2 - 10.1016/j.immuni.2022.07.012

DO - 10.1016/j.immuni.2022.07.012

M3 - Comment/debate

C2 - 35947974

AN - SCOPUS:85135953267

SN - 1074-7613

VL - 55

SP - 1329

EP - 1331

JO - Immunity

JF - Immunity

IS - 8

ER -

FoxP3 forkhead dimer: Don't swap me now

Abstract

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