Four-dimensional optoacoustic temperature mapping in laser-induced thermotherapy

Francisco Javier Oyaga Landa, Xosé Luís Deán-Ben, Ronald Sroka, Daniel Razansky

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

Photoablative laser therapy is in common use for selective destruction of malignant masses, vascular and brain abnormalities. Tissue ablation and coagulation are irreversible processes occurring shortly after crossing a certain thermal exposure threshold. As a result, accurate mapping of the temperature field is essential for optimizing the outcome of these clinical interventions. Here we demonstrate four-dimensional optoacoustic temperature mapping of the entire photoablated region. Accuracy of the method is investigated in tissue-mimicking phantom experiments. Deviations of the volumetric optoacoustic temperature readings provided at 40ms intervals remained below 10% for temperature elevations above 3°C, as validated by simultaneous thermocouple measurements. The excellent spatio-temporal resolution of the new temperature monitoring approach aims at improving safety and efficacy of laser-based photothermal procedures.

Original languageEnglish
Title of host publicationPhotons Plus Ultrasound
Subtitle of host publicationImaging and Sensing 2018
EditorsLihong V. Wang, Alexander A. Oraevsky
PublisherSPIE
ISBN (Electronic)9781510614734
DOIs
StatePublished - 2018
EventPhotons Plus Ultrasound: Imaging and Sensing 2018 - San Francisco, United States
Duration: 28 Jan 20181 Feb 2018

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10494
ISSN (Print)1605-7422

Conference

ConferencePhotons Plus Ultrasound: Imaging and Sensing 2018
Country/TerritoryUnited States
CitySan Francisco
Period28/01/181/02/18

Keywords

  • Ablation of Tissue
  • Optoacoustic Tomography
  • Temperature
  • Thermal Treatments

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