FMT-XCT: Fluorescence molecular tomography and X-ray CT reconstruction using a priori information

A. B.F. Ale, E. Söhngen, R. B. Schulz, V. Ntziachristos

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We have recently developed a hybrid Fluorescence Molecular Tomography - X-ray Computed Tomography (FMT-XCT) system that operates with a common gantry using free-space implementation of CCD camera measurements. In this study several methods were investigated for including structural information from X-ray computed tomography in the FMT reconstruction problem as a regularization term. The performance of these different methods on data obtained with the FMT-XCT system from a brain imaging study on euthanized mice is showcased and optimal inversion scenarios are discussed.

Original languageEnglish
Title of host publicationWorld Congress on Medical Physics and Biomedical Engineering
Subtitle of host publicationDiagnostic Imaging
PublisherSpringer Verlag
Pages350-351
Number of pages2
Edition2
ISBN (Print)9783642038785
DOIs
StatePublished - 2009
EventWorld Congress on Medical Physics and Biomedical Engineering: Diagnostic Imaging - Munich, Germany
Duration: 7 Sep 200912 Sep 2009

Publication series

NameIFMBE Proceedings
Number2
Volume25
ISSN (Print)1680-0737

Conference

ConferenceWorld Congress on Medical Physics and Biomedical Engineering: Diagnostic Imaging
Country/TerritoryGermany
CityMunich
Period7/09/0912/09/09

Keywords

  • Fluorescence molecular tomography
  • Hybrid imaging
  • Reconstruction
  • Regularization

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