Fluorescent protein imaging with multispectral optoacoustic tomography

Daniel Razansky, Martin Distel, Claudio Vinegoni, Rui Ma, Reinhard Köster, Vasilis Ntziachristos

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

In this work, we have developed a selective-plane illumination multispectral optoacoustic tomography (MSOT) technique for high-resolution whole-body visualization of intact optically diffusive organisms whose sizes may vary from sub-millimeter up to a centimeter range and beyond. By combining multi-wavelength illumination, the method is shown capable of resolving tissue-specific expression of fluorescent proteins and other molecular biomarkers located deep in living optically diffuse tissues.

Original languageEnglish
Title of host publicationPhotons Plus Ultrasound
Subtitle of host publicationImaging and Sensing 2010
DOIs
StatePublished - 2010
EventPhotons Plus Ultrasound: Imaging and Sensing 2010 - San Francisco, CA, United States
Duration: 24 Jan 201026 Jan 2010

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7564
ISSN (Print)1605-7422

Conference

ConferencePhotons Plus Ultrasound: Imaging and Sensing 2010
Country/TerritoryUnited States
CitySan Francisco, CA
Period24/01/1026/01/10

Keywords

  • Fluorescent proteins
  • Molecular imaging
  • Optoacoustics
  • Photoacoustic tomography
  • Small animals

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