First palladium-catalyzed aminations of aryl chlorides

Matthias Beller, Thomas H. Riermeier, Claus Peter Reisinger, Wolfgang A. Herrmann

Research output: Contribution to journalArticlepeer-review

103 Scopus citations

Abstract

The palladium-catalyzed coupling reaction of aryl chlorides with various amines has been studied for the first time. Crucial for the success of this C-N bond forming reaction is the use of potassium tert-butoxide as base. Turn over numbers up to 900 and yields up to 80% have been obtained.

Original languageEnglish
Pages (from-to)2073-2074
Number of pages2
JournalTetrahedron Letters
Volume38
Issue number12
DOIs
StatePublished - 24 Mar 1997

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