TY - JOUR
T1 - Finite element investigation of stentless pericardial aortic valves
T2 - Relevance of leaflet geometry
AU - Xiong, Fang Li
AU - Goetz, Wolfgang A.
AU - Chong, Chuh Khiun
AU - Chua, Yeow Leng
AU - Pfeifer, Stefan
AU - Wintermantel, Erich
AU - Yeo, Joon Hock
PY - 2010/5
Y1 - 2010/5
N2 - Recent developments in aortic valve replacement include the truly stentless pericardial bioprostheses with single point attached commissures (SPAC) implantation technique. The leaflet geometry available for the SPAC valves can either be a simple tubular or a complex three-dimensional structure molded using specially designed molds. Our main objective was to compare these two leaflet designs, the tubular vs. the molded, by dynamic finite element simulation. Time-varying physiological pressure loadings over a full cardiac cycle were simulated using ABAQUS. Dynamic leaflet behavior, leaflet coaptation parameters, and stress distribution were compared. The maximum effective valve orifice area during systole is 633.5 mm2 in the molded valve vs. 400.6 mm 2 in the tubular valve, and the leaflet coaptation height during diastole is 4.5 mm in the former, in contrast to 1.6 mm in the latter. Computed compressive stress indicates high magnitudes at the commissures and inter-leaflet margins of the tubular valve, the highest being 3.83 MPa, more than twice greater than 1.80 MPa in the molded valve. The molded leaflet design which resembles the native valve exerts a positive influence on the mechanical performance of the SPAC pericardial valves compared with the simple tubular design. This may suggest enhanced valve efficacy and durability.
AB - Recent developments in aortic valve replacement include the truly stentless pericardial bioprostheses with single point attached commissures (SPAC) implantation technique. The leaflet geometry available for the SPAC valves can either be a simple tubular or a complex three-dimensional structure molded using specially designed molds. Our main objective was to compare these two leaflet designs, the tubular vs. the molded, by dynamic finite element simulation. Time-varying physiological pressure loadings over a full cardiac cycle were simulated using ABAQUS. Dynamic leaflet behavior, leaflet coaptation parameters, and stress distribution were compared. The maximum effective valve orifice area during systole is 633.5 mm2 in the molded valve vs. 400.6 mm 2 in the tubular valve, and the leaflet coaptation height during diastole is 4.5 mm in the former, in contrast to 1.6 mm in the latter. Computed compressive stress indicates high magnitudes at the commissures and inter-leaflet margins of the tubular valve, the highest being 3.83 MPa, more than twice greater than 1.80 MPa in the molded valve. The molded leaflet design which resembles the native valve exerts a positive influence on the mechanical performance of the SPAC pericardial valves compared with the simple tubular design. This may suggest enhanced valve efficacy and durability.
KW - Coaptation area
KW - Coaptation height
KW - Compressive stress
KW - Dynamic leaflet behavior
KW - Effective valve orifice area
KW - Single point attached commissures
KW - Valve molds
UR - http://www.scopus.com/inward/record.url?scp=77952012028&partnerID=8YFLogxK
U2 - 10.1007/s10439-010-9940-6
DO - 10.1007/s10439-010-9940-6
M3 - Article
C2 - 20213213
AN - SCOPUS:77952012028
SN - 0090-6964
VL - 38
SP - 1908
EP - 1918
JO - Annals of Biomedical Engineering
JF - Annals of Biomedical Engineering
IS - 5
ER -