Fiktion und fakten bei der multimodalen therapie des rektumkarzinoms

A. Ulrich; J. Weitz; H. Friess; M. Büchler

doi:10.1055/s-2006-921552

Fiktion und fakten bei der multimodalen therapie des rektumkarzinoms

Translated title of the contribution: Fiction and facts about multi-modal therapy in rectal cancer

A. Ulrich, J. Weitz, H. Friess, M. Büchler

Heidelberg University

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

The prognosis of patients with rectal cancer has been improved significantly after introduction of the total mesorectal excision (TME). Just by performing TME, the local recurrence rates could be decreased to less than 10%, independent of multi-modal therapeutic concepts. In contrast, the local recurrence rate reached 4 to 55% (median 20%) in a German multicenter study in 1995 prior to the nationwide introduction of TME. The goal of this overview is to compare the different concepts in the multi-modal therapy of rectal cancer with their advantages and disadvantages based on the current literature. Mentioned will be local recurrence rates and survival, but also toxicity, costs and acceptance of patients. Furthermore, a preview is given about future developments.

Translated title of the contribution	Fiction and facts about multi-modal therapy in rectal cancer
Original language	German
Pages (from-to)	134-139
Number of pages	6
Journal	Zentralblatt fur Chirurgie - Zeitschrift fur Allgemeine, Viszeral- und Gefasschirurgie
Volume	131
Issue number	2
DOIs	https://doi.org/10.1055/s-2006-921552
State	Published - Apr 2006
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1055/s-2006-921552

Cite this

@article{24f984a55b8f43b58a996c2bfec5cd6e,

title = "Fiktion und fakten bei der multimodalen therapie des rektumkarzinoms",

abstract = "The prognosis of patients with rectal cancer has been improved significantly after introduction of the total mesorectal excision (TME). Just by performing TME, the local recurrence rates could be decreased to less than 10%, independent of multi-modal therapeutic concepts. In contrast, the local recurrence rate reached 4 to 55% (median 20%) in a German multicenter study in 1995 prior to the nationwide introduction of TME. The goal of this overview is to compare the different concepts in the multi-modal therapy of rectal cancer with their advantages and disadvantages based on the current literature. Mentioned will be local recurrence rates and survival, but also toxicity, costs and acceptance of patients. Furthermore, a preview is given about future developments.",

keywords = "Multimodal treatment, Radiotherapy, Rectal carcinoma, Short-term radiotherapy, Total mesorectal excision",

author = "A. Ulrich and J. Weitz and H. Friess and M. B{\"u}chler",

year = "2006",

month = apr,

doi = "10.1055/s-2006-921552",

language = "Deutsch",

volume = "131",

pages = "134--139",

journal = "Zentralblatt fur Chirurgie - Zeitschrift fur Allgemeine, Viszeral- und Gefasschirurgie",

issn = "0044-409X",

publisher = "Georg Thieme Verlag",

number = "2",

}

TY - JOUR

T1 - Fiktion und fakten bei der multimodalen therapie des rektumkarzinoms

AU - Ulrich, A.

AU - Weitz, J.

AU - Friess, H.

AU - Büchler, M.

PY - 2006/4

Y1 - 2006/4

N2 - The prognosis of patients with rectal cancer has been improved significantly after introduction of the total mesorectal excision (TME). Just by performing TME, the local recurrence rates could be decreased to less than 10%, independent of multi-modal therapeutic concepts. In contrast, the local recurrence rate reached 4 to 55% (median 20%) in a German multicenter study in 1995 prior to the nationwide introduction of TME. The goal of this overview is to compare the different concepts in the multi-modal therapy of rectal cancer with their advantages and disadvantages based on the current literature. Mentioned will be local recurrence rates and survival, but also toxicity, costs and acceptance of patients. Furthermore, a preview is given about future developments.

AB - The prognosis of patients with rectal cancer has been improved significantly after introduction of the total mesorectal excision (TME). Just by performing TME, the local recurrence rates could be decreased to less than 10%, independent of multi-modal therapeutic concepts. In contrast, the local recurrence rate reached 4 to 55% (median 20%) in a German multicenter study in 1995 prior to the nationwide introduction of TME. The goal of this overview is to compare the different concepts in the multi-modal therapy of rectal cancer with their advantages and disadvantages based on the current literature. Mentioned will be local recurrence rates and survival, but also toxicity, costs and acceptance of patients. Furthermore, a preview is given about future developments.

KW - Multimodal treatment

KW - Radiotherapy

KW - Rectal carcinoma

KW - Short-term radiotherapy

KW - Total mesorectal excision

UR - http://www.scopus.com/inward/record.url?scp=33646235161&partnerID=8YFLogxK

U2 - 10.1055/s-2006-921552

DO - 10.1055/s-2006-921552

M3 - Übersichtsartikel

C2 - 16612780

AN - SCOPUS:33646235161

SN - 0044-409X

VL - 131

SP - 134

EP - 139

JO - Zentralblatt fur Chirurgie - Zeitschrift fur Allgemeine, Viszeral- und Gefasschirurgie

JF - Zentralblatt fur Chirurgie - Zeitschrift fur Allgemeine, Viszeral- und Gefasschirurgie

IS - 2

ER -

Fiktion und fakten bei der multimodalen therapie des rektumkarzinoms

Abstract

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this