FBXL6 is a vulnerability in AML and unmasks proteolytic cleavage as a major experimental pitfall in myeloid cells

Anna Sperk; Antje Gabriel; Daniela Koch; Abirami Augsburger; Victoria Sanchez; David Brockelt; Rupert Öllinger; Thomas Engleitner; Piero Giansanti; Romina Ludwig; Priska Auf der Maur; Wencke Walter; Torsten Haferlach; Irmela Jeremias; Roland Rad; Barbara Steigenberger; Bernhard Kuster; Ruth Eichner; Florian Bassermann

doi:10.1038/s41375-024-02345-0

FBXL6 is a vulnerability in AML and unmasks proteolytic cleavage as a major experimental pitfall in myeloid cells

Anna Sperk
, Antje Gabriel
, Daniela Koch
, Abirami Augsburger
, Victoria Sanchez
, David Brockelt
, Rupert Öllinger
, Thomas Engleitner
, Piero Giansanti
, Romina Ludwig
, Priska Auf der Maur
, Wencke Walter
, Torsten Haferlach
, Irmela Jeremias
, Roland Rad
, Barbara Steigenberger
, Bernhard Kuster
, Ruth Eichner
, Florian Bassermann

Research output: Contribution to journal › Letter › peer-review

2 Scopus citations

Original language	English
Pages (from-to)	2027-2031
Number of pages	5
Journal	Leukemia
Volume	38
Issue number	9
DOIs	https://doi.org/10.1038/s41375-024-02345-0
State	Published - Sep 2024

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10.1038/s41375-024-02345-0

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Sperk, A., Gabriel, A., Koch, D., Augsburger, A., Sanchez, V., Brockelt, D., Öllinger, R., Engleitner, T., Giansanti, P., Ludwig, R., Auf der Maur, P., Walter, W., Haferlach, T., Jeremias, I., Rad, R., Steigenberger, B., Kuster, B., Eichner, R., & Bassermann, F. (2024). FBXL6 is a vulnerability in AML and unmasks proteolytic cleavage as a major experimental pitfall in myeloid cells. Leukemia, 38(9), 2027-2031. https://doi.org/10.1038/s41375-024-02345-0

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title = "FBXL6 is a vulnerability in AML and unmasks proteolytic cleavage as a major experimental pitfall in myeloid cells",

author = "Anna Sperk and Antje Gabriel and Daniela Koch and Abirami Augsburger and Victoria Sanchez and David Brockelt and Rupert {\"O}llinger and Thomas Engleitner and Piero Giansanti and Romina Ludwig and \{Auf der Maur\}, Priska and Wencke Walter and Torsten Haferlach and Irmela Jeremias and Roland Rad and Barbara Steigenberger and Bernhard Kuster and Ruth Eichner and Florian Bassermann",

year = "2024",

month = sep,

doi = "10.1038/s41375-024-02345-0",

language = "English",

volume = "38",

pages = "2027--2031",

journal = "Leukemia",

issn = "0887-6924",

publisher = "Springer Nature",

number = "9",

}

Sperk, A, Gabriel, A, Koch, D, Augsburger, A, Sanchez, V, Brockelt, D, Öllinger, R, Engleitner, T, Giansanti, P, Ludwig, R, Auf der Maur, P, Walter, W, Haferlach, T, Jeremias, I, Rad, R, Steigenberger, B, Kuster, B, Eichner, R & Bassermann, F 2024, 'FBXL6 is a vulnerability in AML and unmasks proteolytic cleavage as a major experimental pitfall in myeloid cells', Leukemia, vol. 38, no. 9, pp. 2027-2031. https://doi.org/10.1038/s41375-024-02345-0

TY - JOUR

T1 - FBXL6 is a vulnerability in AML and unmasks proteolytic cleavage as a major experimental pitfall in myeloid cells

AU - Sperk, Anna

AU - Gabriel, Antje

AU - Koch, Daniela

AU - Augsburger, Abirami

AU - Sanchez, Victoria

AU - Brockelt, David

AU - Öllinger, Rupert

AU - Engleitner, Thomas

AU - Giansanti, Piero

AU - Ludwig, Romina

AU - Auf der Maur, Priska

AU - Walter, Wencke

AU - Haferlach, Torsten

AU - Jeremias, Irmela

AU - Rad, Roland

AU - Steigenberger, Barbara

AU - Kuster, Bernhard

AU - Eichner, Ruth

AU - Bassermann, Florian

PY - 2024/9

Y1 - 2024/9

UR - https://www.scopus.com/pages/publications/85198703180

U2 - 10.1038/s41375-024-02345-0

DO - 10.1038/s41375-024-02345-0

M3 - Letter

AN - SCOPUS:85198703180

SN - 0887-6924

VL - 38

SP - 2027

EP - 2031

JO - Leukemia

JF - Leukemia

IS - 9

ER -

FBXL6 is a vulnerability in AML and unmasks proteolytic cleavage as a major experimental pitfall in myeloid cells

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