FBXL6 is a vulnerability in AML and unmasks proteolytic cleavage as a major experimental pitfall in myeloid cells

Anna Sperk; Antje Gabriel; Daniela Koch; Abirami Augsburger; Victoria Sanchez; David Brockelt; Rupert Öllinger; Thomas Engleitner; Piero Giansanti; Romina Ludwig; Priska Auf der Maur; Wencke Walter; Torsten Haferlach; Irmela Jeremias; Roland Rad; Barbara Steigenberger; Bernhard Kuster; Ruth Eichner; Florian Bassermann

doi:10.1038/s41375-024-02345-0

FBXL6 is a vulnerability in AML and unmasks proteolytic cleavage as a major experimental pitfall in myeloid cells

Anna Sperk, Antje Gabriel, Daniela Koch, Abirami Augsburger, Victoria Sanchez, David Brockelt, Rupert Öllinger, Thomas Engleitner, Piero Giansanti, Romina Ludwig, Priska Auf der Maur, Wencke Walter, Torsten Haferlach, Irmela Jeremias, Roland Rad, Barbara Steigenberger, Bernhard Kuster, Ruth Eichner, Florian Bassermann

Research output: Contribution to journal › Letter › peer-review

Original language	English
Pages (from-to)	2027-2031
Number of pages	5
Journal	Leukemia
Volume	38
Issue number	9
DOIs	https://doi.org/10.1038/s41375-024-02345-0
State	Published - Sep 2024

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Sperk, A., Gabriel, A., Koch, D., Augsburger, A., Sanchez, V., Brockelt, D., Öllinger, R., Engleitner, T., Giansanti, P., Ludwig, R., Auf der Maur, P., Walter, W., Haferlach, T., Jeremias, I., Rad, R., Steigenberger, B., Kuster, B., Eichner, R., & Bassermann, F. (2024). FBXL6 is a vulnerability in AML and unmasks proteolytic cleavage as a major experimental pitfall in myeloid cells. Leukemia, 38(9), 2027-2031. https://doi.org/10.1038/s41375-024-02345-0

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title = "FBXL6 is a vulnerability in AML and unmasks proteolytic cleavage as a major experimental pitfall in myeloid cells",

author = "Anna Sperk and Antje Gabriel and Daniela Koch and Abirami Augsburger and Victoria Sanchez and David Brockelt and Rupert {\"O}llinger and Thomas Engleitner and Piero Giansanti and Romina Ludwig and {Auf der Maur}, Priska and Wencke Walter and Torsten Haferlach and Irmela Jeremias and Roland Rad and Barbara Steigenberger and Bernhard Kuster and Ruth Eichner and Florian Bassermann",

year = "2024",

month = sep,

doi = "10.1038/s41375-024-02345-0",

language = "English",

volume = "38",

pages = "2027--2031",

journal = "Leukemia",

issn = "0887-6924",

publisher = "Springer Nature",

number = "9",

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Sperk, A, Gabriel, A, Koch, D, Augsburger, A, Sanchez, V, Brockelt, D, Öllinger, R, Engleitner, T, Giansanti, P, Ludwig, R, Auf der Maur, P, Walter, W, Haferlach, T, Jeremias, I, Rad, R, Steigenberger, B, Kuster, B, Eichner, R & Bassermann, F 2024, 'FBXL6 is a vulnerability in AML and unmasks proteolytic cleavage as a major experimental pitfall in myeloid cells', Leukemia, vol. 38, no. 9, pp. 2027-2031. https://doi.org/10.1038/s41375-024-02345-0

TY - JOUR

T1 - FBXL6 is a vulnerability in AML and unmasks proteolytic cleavage as a major experimental pitfall in myeloid cells

AU - Sperk, Anna

AU - Gabriel, Antje

AU - Koch, Daniela

AU - Augsburger, Abirami

AU - Sanchez, Victoria

AU - Brockelt, David

AU - Öllinger, Rupert

AU - Engleitner, Thomas

AU - Giansanti, Piero

AU - Ludwig, Romina

AU - Auf der Maur, Priska

AU - Walter, Wencke

AU - Haferlach, Torsten

AU - Jeremias, Irmela

AU - Rad, Roland

AU - Steigenberger, Barbara

AU - Kuster, Bernhard

AU - Eichner, Ruth

AU - Bassermann, Florian

PY - 2024/9

Y1 - 2024/9

UR - http://www.scopus.com/inward/record.url?scp=85198703180&partnerID=8YFLogxK

U2 - 10.1038/s41375-024-02345-0

DO - 10.1038/s41375-024-02345-0

M3 - Letter

AN - SCOPUS:85198703180

SN - 0887-6924

VL - 38

SP - 2027

EP - 2031

JO - Leukemia

JF - Leukemia

IS - 9

ER -

FBXL6 is a vulnerability in AML and unmasks proteolytic cleavage as a major experimental pitfall in myeloid cells

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