Fatal neonatal respiratory failure in an infant with congenital hypothyroidism due to haploinsufficiency of the NKX2-1 gene: Alteration of pulmonary surfactant homeostasis

Keyphrases

• Haploinsufficiency 100%
• Surfactant Homeostasis 100%
• Gene Alteration 100%
• Neonatal Respiratory Distress Syndrome 100%
• Nkx2.1 100%
• Congenital Hypothyroidism 100%
• Pulmonary Surfactant 100%
• NKX2-1 Gene 100%
• Respiratory Failure 66%
• Lipid Homeostasis 66%
• Congenital Disorders 33%
• Respiratory Disease 33%
• Bronchoalveolar Lavage Fluid 33%
• Term Infants 33%
• Protein Homeostasis 33%
• Respiratory Insufficiency 33%
• Gene Analysis 33%
• Surfactant Protein A (SP-A) 33%
• Fatal Outcome 33%
• Surfactant Protein B 33%
• Thyroid Transcription factor-1 (TTF-1) 33%
• Hypothyroidism 33%
• Ventilatory Support 33%
• ABCA3 33%
• SP-C 33%
• Surfactant Lipids 33%
• Surfactant Phospholipids 33%
• Brain-lung-thyroid Syndrome 33%
• Benign Hereditary Chorea 33%
• SFTPB 33%
• SFTPC 33%

Medicine and Dentistry

• Haploinsufficiency 100%
• Gene Mutation 100%
• Homeostasis 100%
• Respiratory Failure 100%
• Pulmonary Surfactant 100%
• Congenital Hypothyroidism 100%
• Neonatal Infant 50%
• Lipid Homeostasis 50%
• Allele 25%
• Respiratory Disease 25%
• Huntington's Disease 25%
• Lung 25%
• Congenital Disorder 25%
• Bronchoalveolar Lavage Fluid 25%
• Fatality 25%
• Homeobox Protein Nkx 2.1 25%
• Hypothyroidism 25%
• Protein Homeostasis 25%
• Phospholipid 25%
• Surfactant Protein C 25%
• Surfactant 25%
• Surfactant Protein 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Pulmonary Surfactant 100%
• Congenital Hypothyroidism 100%
• Respiratory Failure 100%
• Surfactant 50%
• Syndrome 25%
• Huntington Chorea 25%
• Fatality 25%
• Respiratory Tract Disease 25%
• Homeobox Protein Nkx 2.1 25%
• Phospholipid 25%
• Congenital Disorder 25%
• Hypothyroidism 25%
• Surfactant Protein C 25%