Fast three-dimensional sodium imaging of human brain

Sascha Köhler, Christine Preibisch, Mathias Nittka, Axel Haase

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

A three-dimensional sodium imaging technique with a minimum echo time of 0.9 ms is described in a 2.0 Tesla whole-body system. The relaxation behaviour in vivo of sodium was analysed: a fast T*2 relaxation component between 1.2 and 1.6 ms and a slow T*2 relaxation component between 7.1 ms and 8.4 ms were quantified in brain tissue of three volunteers. Three-dimensional sodium images of the human brain were acquired in 8.5 min with a resolution of 4.7 × 4.7 × 10 mm (0.2 cc voxel size) and a signal-to-noise ratio of 20 in brain tissue and 30 in cerebrospinal fluid.

Original languageEnglish
Pages (from-to)63-69
Number of pages7
JournalMagnetic Resonance Materials in Physics, Biology and Medicine
Volume13
Issue number2
DOIs
StatePublished - 2001
Externally publishedYes

Keywords

  • Biexponential relaxation
  • Human brain
  • Magnetic resonance imaging
  • Sodium imaging

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