Facile Synthesis of a β(1‐3)‐Linked gal‐galactal Disaccharide and Its Use in N‐Iodosuccinimide‐Activated O‐Glycopeptide Synthesis

The fact that compound 1 can now be synthesized in four steps with an overall yield of 21 % should ensure its broader utilization in the NIS‐activated synthesis of glycopeptides. The key intermediate in the process is the selectively protected galactaldehyde derivative 2.1 reacts not only with the universally applicable Fmoc‐Ser‐OBzl subunit but also with a cyclic glycophorin‐A fragment. (Figure Presented.)