Facile and efficient reduction of ketones in the presence of zinc catalysts modified by phenol ligands

Stephan Enthaler; Björn Eckhardt; Shigeyoshi Inoue; Elisabeth Irran; Matthias Driess

doi:10.1002/asia.201000317

Facile and efficient reduction of ketones in the presence of zinc catalysts modified by phenol ligands

Stephan Enthaler
, Björn Eckhardt
, Shigeyoshi Inoue
, Elisabeth Irran
, Matthias Driess

Technische Universität Berlin

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

Abstract

In the present study, the zinc-catalyzed hydrosilylation of various ketones to give their corresponding alcohols has been examined in detail. Diethyl zinc that can be modified by easily accessible phenol ligands allows the efficient reduction of various aryl and alkyl ketones. By using a practical in situ catalyst, excellent turnover frequencies up to 1000 h^-1 and a broad functional group tolerance were achieved.

Original language	English
Pages (from-to)	2027-2035
Number of pages	9
Journal	Chemistry - An Asian Journal
Volume	5
Issue number	9
DOIs	https://doi.org/10.1002/asia.201000317
State	Published - 3 Sep 2010
Externally published	Yes

Keywords

Catalysis
Hydrosilyla-tion
Ketones
Phenol ligands
Zinc

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10.1002/asia.201000317

Cite this

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title = "Facile and efficient reduction of ketones in the presence of zinc catalysts modified by phenol ligands",

abstract = "In the present study, the zinc-catalyzed hydrosilylation of various ketones to give their corresponding alcohols has been examined in detail. Diethyl zinc that can be modified by easily accessible phenol ligands allows the efficient reduction of various aryl and alkyl ketones. By using a practical in situ catalyst, excellent turnover frequencies up to 1000 h-1 and a broad functional group tolerance were achieved.",

keywords = "Catalysis, Hydrosilyla-tion, Ketones, Phenol ligands, Zinc",

author = "Stephan Enthaler and Bj{\"o}rn Eckhardt and Shigeyoshi Inoue and Elisabeth Irran and Matthias Driess",

year = "2010",

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T1 - Facile and efficient reduction of ketones in the presence of zinc catalysts modified by phenol ligands

AU - Enthaler, Stephan

AU - Eckhardt, Björn

AU - Inoue, Shigeyoshi

AU - Irran, Elisabeth

AU - Driess, Matthias

PY - 2010/9/3

Y1 - 2010/9/3

N2 - In the present study, the zinc-catalyzed hydrosilylation of various ketones to give their corresponding alcohols has been examined in detail. Diethyl zinc that can be modified by easily accessible phenol ligands allows the efficient reduction of various aryl and alkyl ketones. By using a practical in situ catalyst, excellent turnover frequencies up to 1000 h-1 and a broad functional group tolerance were achieved.

AB - In the present study, the zinc-catalyzed hydrosilylation of various ketones to give their corresponding alcohols has been examined in detail. Diethyl zinc that can be modified by easily accessible phenol ligands allows the efficient reduction of various aryl and alkyl ketones. By using a practical in situ catalyst, excellent turnover frequencies up to 1000 h-1 and a broad functional group tolerance were achieved.

KW - Catalysis

KW - Hydrosilyla-tion

KW - Ketones

KW - Phenol ligands

KW - Zinc

UR - https://www.scopus.com/pages/publications/77956476695

U2 - 10.1002/asia.201000317

DO - 10.1002/asia.201000317

M3 - Article

AN - SCOPUS:77956476695

SN - 1861-4728

VL - 5

SP - 2027

EP - 2035

JO - Chemistry - An Asian Journal

JF - Chemistry - An Asian Journal

IS - 9

ER -

Facile and efficient reduction of ketones in the presence of zinc catalysts modified by phenol ligands

Abstract

Keywords

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